Pucket Jonathan D, Allbaugh Rachel A, Higginbotham Mary L, Rankin Amy J, Teixeira Leandro
Department of Veterinary Clinical Sciences, College of Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Open Vet J. 2017;7(2):132-138. doi: 10.4314/ovj.v7i2.9. Epub 2017 May 22.
A 10-year-old Labrador Retriever who had been undergoing therapy for a recurrent hemangiopericytoma of the right flank presented to the Kansas State University Ophthalmology service for evaluation of a painful left eye. Examination revealed secondary glaucoma and irreversible blindness of the affected eye and multifocal chorioretinal lesions in the fellow eye. Therapeutic and diagnostic enucleation of the left eye was performed and histopathologic examination demonstrated the presence of a presumed metastatic spindle cell sarcoma. Further immunohistochemical staining confirmed the intraocular neoplasia to be metastatic spread from the previously removed flank mass. Rapid progression in size and number of chorioretinal lesions in the right eye was noted in the post-operative period until the patient was euthanized one month after surgery. This case report is the first to document intraocular metastasis of hemangiopericytoma in a veterinary patient.
一只10岁的拉布拉多猎犬因右侧腹复发性血管外皮细胞瘤接受治疗，后前往堪萨斯州立大学眼科就诊，以评估其疼痛的左眼。检查发现患眼继发性青光眼和不可逆性失明，对侧眼有多灶性脉络膜视网膜病变。对左眼进行了治疗性和诊断性眼球摘除术，组织病理学检查显示存在推测的转移性梭形细胞肉瘤。进一步的免疫组化染色证实眼内肿瘤是先前切除的侧腹肿块的转移扩散。术后观察到右眼脉络膜视网膜病变的大小和数量迅速进展，直到术后一个月对该犬实施安乐死。本病例报告首次记录了兽医患者血管外皮细胞瘤的眼内转移。
