BioQuant/COS, Heidelberg University, Heidelberg, Germany.
Biocomplexity Institute of Virginia Tech, Blacksburg, VA, USA.
J Biotechnol. 2017 Nov 10;261:215-220. doi: 10.1016/j.jbiotec.2017.06.1200. Epub 2017 Jun 24.
COPASI is software used for the creation, modification, simulation and computational analysis of kinetic models in various fields. It is open-source, available for all major platforms and provides a user-friendly graphical user interface, but is also controllable via the command line and scripting languages. These are likely reasons for its wide acceptance. We begin this review with a short introduction describing the general approaches and techniques used in computational modeling in the biosciences. Next we introduce the COPASI package, and its capabilities, before looking at typical applications of COPASI in biotechnology.
COPASI 是一款用于创建、修改、模拟和计算分析各种领域的动力学模型的软件。它是开源的，适用于所有主要平台，并提供用户友好的图形用户界面，但也可以通过命令行和脚本语言进行控制。这些可能是它被广泛接受的原因。我们从简短介绍开始，介绍生物科学中计算建模使用的一般方法和技术。接下来，我们将介绍 COPASI 软件包及其功能，然后再研究 COPASI 在生物技术中的典型应用。
