Meseret Maru, Shimeka Alemayehu, Bekele Alemayehu
Amhara National Regional State Health Bureau, East Gojjam Zonal Health Department, Bahir-Dar, Ethiopia.
Department of Epidemiology and Biostatistics, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
AIDS Res Treat. 2017;2017:3261205. doi: 10.1155/2017/3261205. Epub 2017 Jun 5.
Globally, death of women due to HIV/AIDS related causes during pregnancy or within 42 days after pregnancy was estimated to be 37,000. In Ethiopia, 42,900 pregnant women living with HIV gave birth in the year 2011. This study was aimed to assess incidence and predictors of pregnancy among women on ART in Debre Markos Referral Hospital, Northwest Ethiopia. A retrospective cohort study was conducted using data recorded from September 2011 to August 2015. Data was extracted from February to March, 2016, from 1,239 records and analyzed using SPSS version 16. A Kaplan-Meier survival analysis was used to estimate the probabilities of being pregnant. The Cox proportional hazards model was done and results were expressed using hazard ratios with 95% CI. A total of 1,239 women on ART were included in the study. The incidence of pregnancy was 49.2 per 1,000 person-years. Living in rural, being married, being widowed, being unemployed, and having <2 children at enrollment were found to be positively associated with being pregnant. The incidence of pregnancy among women on ART was found to be considerable. Provision of family planning and other reproductive health interventions have to be coupled with the ART service to address the problem.
全球范围内，估计有37000名妇女在孕期或产后42天内因与艾滋病毒/艾滋病相关的原因死亡。在埃塞俄比亚，2011年有42900名感染艾滋病毒的孕妇分娩。本研究旨在评估埃塞俄比亚西北部德布雷马科斯转诊医院接受抗逆转录病毒治疗（ART）的妇女的妊娠发生率及预测因素。采用回顾性队列研究，使用2011年9月至2015年8月记录的数据。2016年2月至3月从1239份记录中提取数据，并使用SPSS 16版进行分析。采用Kaplan-Meier生存分析来估计妊娠概率。进行了Cox比例风险模型分析，结果以风险比及95%置信区间表示。共有1239名接受抗逆转录病毒治疗的妇女纳入研究。妊娠发生率为每1000人年49.2例。研究发现，居住在农村、已婚、丧偶、失业以及入组时子女数<2个与妊娠呈正相关。接受抗逆转录病毒治疗的妇女妊娠发生率较高。必须将计划生育和其他生殖健康干预措施与抗逆转录病毒治疗服务相结合，以解决这一问题。
