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类风湿性关节炎患者双髁混合膝关节置换术中非骨水泥型股骨组件:10年生存率分析

Cementless femoral components in bicondylar hybrid knee arthroplasty in patients with rheumatoid arthritis: A 10-year survivorship analysis.

作者信息

Hotfiel Thilo, Carl Hans-Dieter, Eibenberger Teresa, Gelse Kolja, Weiß Julian, Jendrissek Andreas, Swoboda Bernd

机构信息

1 Division of Orthopedic Rheumatology, Department of Orthopedic Surgery, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

2 Department of Orthopedic and Trauma Surgery, University Hospital Erlangen, Erlangen, Germany.

出版信息

J Orthop Surg (Hong Kong). 2017 May-Aug;25(2):2309499017716252. doi: 10.1177/2309499017716252.

Abstract

BACKGROUND

Total knee arthroplasty (TKA) has been established as a successful surgical treatment in the late stages of rheumatoid joint destruction. The purpose of this study was to review the clinical outcome and survivorship in rheumatoid arthritis (RA) patients undergoing TKA in hybrid technique with a cementless fixation of the femoral component.

METHODS

We analysed retrospectively 66 RA patients who underwent 72 TKAs (P.F.C. Sigma®). Mean follow-up time was 124 ± 41 months. To evaluate postoperative clinical outcome, knee injury and osteoarthritis outcome score (KOOS) and Oxford knee score (OKS) were assessed. Kaplan-Meier analysis was used to calculate survivorship. The primary outcome was revision for any reason.

RESULTS

Thirty-four patients (36 knees) died and two patients (2 knees) were lost to follow-up. Three patients (four knees) did not agree to participate. Twenty-seven patients (30 knees) were available for assessing clinical scores. The average scores were 85 ± 14 for KOOS and 34 ± 10 for OKS. In three patients (three knees), revision was necessary, including restricted range of motion ( n = 1), instability ( n = 1), and infection ( n = 1). There were no cases of loosening in this cohort study. The survival rates were 100% at 5 years, 97.1% at 10 years (95% CI 89.0-99.2%) and 95.6% at 15 years (95% CI 86.9-98.5%).

CONCLUSIONS

This study confirms that excellent clinical results and a good 10-year survivorship can be obtained with hybrid fixation technique in TKA in the unique population of RA patients.

摘要

背景

全膝关节置换术(TKA)已成为类风湿性关节破坏晚期成功的外科治疗方法。本研究的目的是回顾采用混合技术、股骨组件非骨水泥固定的类风湿性关节炎(RA)患者行TKA后的临床疗效和假体生存率。

方法

我们回顾性分析了66例行72次TKA(P.F.C. Sigma®)的RA患者。平均随访时间为124±41个月。为评估术后临床疗效,采用膝关节损伤和骨关节炎疗效评分(KOOS)及牛津膝关节评分(OKS)。采用Kaplan-Meier分析计算假体生存率。主要结局指标为因任何原因进行的翻修手术。

结果

34例患者(36膝)死亡,2例患者(2膝)失访。3例患者(4膝)不同意参与。27例患者(30膝)可用于评估临床评分。KOOS平均评分为85±14分,OKS平均评分为34±10分。3例患者(3膝)需要翻修,包括活动范围受限(n = 1)、不稳定(n = 1)和感染(n = 1)。在这项队列研究中没有松动病例。5年生存率为100%,10年生存率为97.1%(95%CI 89.0-99.2%),15年生存率为95.6%(95%CI 86.9-98.5%)。

结论

本研究证实,在RA患者这一特殊人群中,TKA采用混合固定技术可获得优异的临床疗效和良好的10年假体生存率。

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