Zhang Zhijun, Ju Enguo, Bing Wei, Wang Zhenzhen, Ren Jinsong, Qu Xiaogang
Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
Chem Commun (Camb). 2017 Jul 25;53(60):8415-8418. doi: 10.1039/c7cc03794e.
A chemically engineered armour is developed for simultaneously improving bioreporter bacterial vitality and shielding infectivity. The armour can help bacteria to resist various insults and even immune phagocytosis. Meanwhile, the bacterial infectivity has proven to be greatly shielded as well. Most importantly, the original bacterial biosensing activity is well preserved, which is competent for sensing trace arsenic in water, serum, and even in vivo.
一种化学工程化的“铠甲”被开发出来，用于同时提高生物报告细菌的活力并屏蔽其传染性。这种“铠甲”可以帮助细菌抵抗各种损伤，甚至免疫吞噬作用。同时，已证明细菌的传染性也得到了极大的屏蔽。最重要的是，原始的细菌生物传感活性得到了很好的保留，这使其能够检测水中、血清中甚至体内的痕量砷。
