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教育与高血压:对全球心血管风险的影响

Education and hypertension: impact on global cardiovascular risk.

作者信息

Di Chiara Tiziana, Scaglione Alessandra, Corrao Salvatore, Argano Christiano, Pinto Antonio, Scaglione Rosario

机构信息

a Department of Internal and Specialist Medicine , University of Palermo , Palermo , Italy.

出版信息

Acta Cardiol. 2017 Oct;72(5):507-513. doi: 10.1080/00015385.2017.1297626. Epub 2017 Jun 28.

Abstract

BACKGROUND

Improving cardiovascular risk prediction continues to be a major challenge and effective prevention of cardiovascular disease. Accordingly, several studies have recently reported on the role of cardiovascular risk education. This study was designed to evaluate the impact of education on global cardiovascular risk in hypertensive patients.

SUBJECTS AND METHODS

The study population consisted of 223 consecutive hypertensive outpatients. Their educational status was categorized according to the number of years of formal education as follows: (1) low education (less than 10 years) and (2) medium-high education (10-15 years).

RESULTS

In both groups, cardiometabolic comorbidities, global cardiovascular risk and echocardiographic measurements were analysed. Less educated hypertensive subjects were characterized by a significantly higher prevalence of patients with metabolic syndrome (MetS) (p < .01), greater global cardiovascular risk (p < .001), and a higher consumption of antihypertensive drugs (p < .01) rather than medium-high educated hypertensive subjects. In the same subjects, a significant increase in microalbuminuria (MA) (p < .01) and a significant decrease in E/A (p < .001) ratio was found. Univariate analysis indicated that global cardiovascular risk correlated directly with waist-hip ratio, mean blood pressure, MA, left ventricular mass index, MetS and inversely with education (r = -0.45; p < .001). Education was independently (p < .001) associated with global CV risk.

CONCLUSIONS

Our data suggest that education may be considered the best predictor of global cardiovascular risk in hypertensives and thus has to be evaluated in the strategies of hypertension and cardiovascular risk management.

摘要

背景

改善心血管疾病风险预测仍然是一项重大挑战,也是有效预防心血管疾病的关键。因此,最近有几项研究报道了心血管疾病风险教育的作用。本研究旨在评估教育对高血压患者整体心血管疾病风险的影响。

对象与方法

研究对象为223例连续就诊的高血压门诊患者。根据正规教育年限将其教育程度分为以下两类:(1)低教育程度(少于10年)和(2)中高教育程度(10 - 15年)。

结果

对两组患者的心脏代谢合并症、整体心血管疾病风险和超声心动图测量结果进行了分析。与中高教育程度的高血压患者相比,低教育程度的高血压患者具有以下特点:代谢综合征(MetS)患者的患病率显著更高(p < 0.01),整体心血管疾病风险更高(p < 0.001),以及降压药物的消耗量更高(p < 0.01)。在同一组患者中,还发现微量白蛋白尿(MA)显著增加(p < 0.01),E/A比值显著降低(p < 0.001)。单因素分析表明,整体心血管疾病风险与腰臀比、平均血压、MA、左心室质量指数、MetS直接相关,与教育程度呈负相关(r = -0.45;p < 0.001)。教育程度与整体心血管疾病风险独立相关(p < 0.001)。

结论

我们的数据表明,教育程度可能被认为是高血压患者整体心血管疾病风险的最佳预测指标,因此在高血压和心血管疾病风险管理策略中必须加以评估。

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