Polhuis Kristel C M M, Wijnen Annemarthe H C, Sierksma Aafje, Calame Wim, Tieland Michael
The Dutch Beer Institute, Wageningen 6701, The Netherlands.
Division of Health and Society, Wageningen University, Wageningen 6706, The Netherlands.
Nutrients. 2017 Jun 28;9(7):660. doi: 10.3390/nu9070660.
With ageing, there is a greater risk of dehydration. This study investigated the diuretic effect of alcoholic beverages varying in alcohol concentration in elderly men. Three alcoholic beverages (beer (AB), wine (AW), and spirits (S)) and their non-alcoholic counterparts (non-alcoholic beer (NAB), non-alcoholic wine (NAW), and water (W)) were tested in a diet-controlled randomized crossover trial. For the alcoholic beverages, alcohol intake equaled a moderate amount of 30 g. An equal volume of beverage was given for the non-alcoholic counterpart. After consumption, the urine output was collected every hour for 4 h and the total 24 h urine output was measured. AW and S resulted in a higher cumulative urine output compared to NAW and W during the first 4 h (effect size: 0.25 mL < 0.003, effect size: 0.18 mL, < 0.001, respectively), but not after the 24h urine collection ( > 0.40, > 0.10). AB and NAB did not differ at any time point (effect size: -0.02 mL > 0.70). For urine osmolality, and the sodium and potassium concentration, the findings were in line. In conclusion, only moderate amounts of stronger alcoholic beverages, such as wine and spirits, resulted in a short and small diuretic effect in elderly men.
随着年龄增长，脱水风险会更高。本研究调查了酒精浓度不同的酒精饮料对老年男性的利尿作用。在一项饮食控制的随机交叉试验中，测试了三种酒精饮料（啤酒（AB）、葡萄酒（AW）和烈酒（S））及其无酒精对应物（无酒精啤酒（NAB）、无酒精葡萄酒（NAW）和水（W））。对于酒精饮料，酒精摄入量相当于30克的适量饮酒量。给无酒精对应物提供等量体积的饮料。饮用后，每小时收集尿量，持续4小时，并测量24小时总尿量。在最初4小时内，与NAW和W相比，AW和S导致更高的累积尿量（效应大小：0.25毫升，<0.003；效应大小：0.18毫升，<0.001），但在24小时尿液收集后没有差异（>0.40，>0.10）。AB和NAB在任何时间点都没有差异（效应大小：-0.02毫升，>0.70）。对于尿渗透压以及钠和钾浓度，研究结果一致。总之，只有适量饮用较强的酒精饮料，如葡萄酒和烈酒，才会对老年男性产生短暂且轻微的利尿作用。
