Felleiter Peter, Krebs Joerg, Haeberli Yvonne, Schmid Wilma, Tesini Stefanie, Perret Claudio
Intensive Care Medicine, Swiss Paraplegic Centre Nottwil, 6207 Nottwil, Switzerland.
J Rehabil Med. 2017 Jul 7;49(7):579-584. doi: 10.2340/16501977-2244.
Prospective cohort study.
To investigate the changes in resting energy expenditure and body composition over time in a cohort of patients with spinal cord injury during acute treatment, rehabilitation, and 2 years after the end of rehabilitation.
Adult patients admitted for acute treatment and rehabilitation after traumatic spinal cord injury were recruited. Measurements of resting energy expenditure and body composition were scheduled at 2, 6, 10 and 14 weeks after spinal cord injury, at the end of rehabilitation, and 2 years later.
Patients' mean age was 38.8 years (standard deviation 14.0). Resting energy expenditure began to decrease up to the 10-week measurement (p = 0.02) and further decreased after the 130-week measurement (p< 0.001). Body weight was already decreased after the 6-week measurement (p< 0.01) and increased after the end of rehabilitation (p = 0.009). Percentage body fat mass showed similar changes.
After an initial decrease in resting energy expenditure, body weight and percentage of body fat, these values levelled off during the rehabilitation period. After the end of the rehabilitation period, body weight and body fat mass increased again to the baseline levels, whereas resting energy expenditure decreased further. These results suggest that rehabilitation programmes should focus on adapting to these foreseeable changes.
前瞻性队列研究。
调查脊髓损伤患者在急性治疗、康复期间以及康复结束后2年里静息能量消耗和身体成分随时间的变化情况。
招募因创伤性脊髓损伤而接受急性治疗和康复的成年患者。在脊髓损伤后2周、6周、10周和14周、康复结束时以及2年后安排静息能量消耗和身体成分的测量。
患者的平均年龄为38.8岁（标准差14.0）。静息能量消耗在第10周测量时开始下降（p = 0.02），在第130周测量后进一步下降（p < 0.001）。体重在第6周测量后已经下降（p < 0.01），在康复结束后增加（p = 0.009）。体脂百分比显示出类似的变化。
在静息能量消耗、体重和体脂百分比最初下降后，这些数值在康复期趋于平稳。康复期结束后，体重和体脂量再次增加至基线水平，而静息能量消耗则进一步下降。这些结果表明康复计划应注重适应这些可预见的变化。
