Lotufo Paulo Andrade, Goulart Alessandra Carvalho, Passos Valéria Maria de Azeredo, Satake Fabio Mitsuhiro, Souza Maria de Fátima Marinho de, França Elizabeth Barbosa, Ribeiro Antônio Luiz Pinho, Bensenõr Isabela Judith Martins
Centro de Pesquisa Clínica e Epidemiológica da Universidade de São Paulo - São Paulo (SP), Brasil.
Faculdade de Medicina da Universidade de São Paulo - São Paulo (SP), Brasil.
Rev Bras Epidemiol. 2017 May;20Suppl 01(Suppl 01):129-141. doi: 10.1590/1980-5497201700050011.
: To verify the time trends of mortality rates, years of lost life (YLL), and years lived with disability (YLD) caused by cerebrovascular disease in Brazil between 1990 and 2015.
: The estimates from the Global Burden of Diseases 2015 were used to analyze the magnitude and trends of mortality rates and disability-adjusted life years (DALY) for cerebrovascular disease (ICD-10: I-60-69) in the 27 units of the Federation between 1990 and 2015. The states were analyzed by the social development index (SDI), based on average income per person, educational attainment at 15 years- old and total fertility rate.
: Despite the increase in the absolute number of deaths due to cerebrovascular disease, the proportion of deaths below 70 years of age has been halved between 1990 and 2015. The acceleration of the reduction was higher among women; and increased from 1990 to 2005, when compared to the period from 2005 to 2015. The risk of death has been halved across the country, but states in the lower SDI tertile had less significant reductions (-1.23 and -1.84% a year) compared to the middle tertile (-1.94 and - 2.22%) and the upper tertile (-2.85 and -2.82%) for men and women, respectively. The years lived with disability also presented a reduction among states, but less expressively.
: Despite the reduction of age-adjusted mortality rates throughout the country, cerebrovascular disease still presents a high disease burden, especially in states with lower socioeconomic development.
验证1990年至2015年期间巴西脑血管疾病所致死亡率、生命损失年数（YLL）和伤残调整生命年（YLD）的时间趋势。
利用《2015年全球疾病负担》的估计数据，分析1990年至2015年期间联邦27个州脑血管疾病（国际疾病分类第10版：I-60-69）的死亡率和伤残调整生命年（DALY）的规模及趋势。根据人均收入、15岁时的教育程度和总生育率，通过社会发展指数（SDI）对各州进行分析。
尽管脑血管疾病导致的死亡绝对数有所增加，但1990年至2015年期间，70岁以下人群的死亡比例减半。女性的下降加速更为明显；与2005年至2015年期间相比，1990年至2005年期间下降加速。全国的死亡风险减半，但社会发展指数处于较低三分位数的州，男性和女性的下降幅度分别为每年-1.23%和-1.84%，低于处于中间三分位数的州（-1.94%和-2.22%）和处于较高三分位数的州（-2.85%和-2.82%）。各州的伤残调整生命年数也有所减少，但不太明显。
尽管全国年龄调整后的死亡率有所下降，但脑血管疾病仍然带来较高的疾病负担，尤其是在社会经济发展较低的州。
