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[肾综合征出血热流行过程的特征]

[Characteristics of the epizootic process in hemorrhagic fever with renal syndrome].

作者信息

Bashkirtsev V N, Ryl'tseva E V, Tkachenko E A, Stepanenko A G

出版信息

Vopr Virusol. 1985 Jul-Aug;30(4):463-8.

PMID:2865854
Abstract

For the first time in the study of epizootology of hemorrhagic fever with the renal syndrome (HFRS) in wild animals data are presented indicating certain relationship between true infection rate of bank voles with HFRS virus and the content of the circulating antigen of HFRS virus and antibody to this virus in these animals. Different age groups of animal populations were shown to have different intensity of immunity: it was more marked in animals of older age groups, and less in young animals. On the contrary, live virus was most frequently found in young animals. It has been shown that for successful isolation of the virus from bank voles it is necessary to take into consideration the characteristics of acute infection in rodents: the presence of HFRS virus antigen in their lung tissue and the lack of antibody to the virus in the blood.

摘要

在野生动物肾综合征出血热(HFRS)流行病学研究中,首次呈现的数据表明,黑线姬鼠感染HFRS病毒的实际感染率与这些动物体内HFRS病毒循环抗原及该病毒抗体含量之间存在一定关系。研究表明,不同年龄组的动物群体具有不同的免疫强度:老龄组动物的免疫强度更明显,幼龄动物的免疫强度则较弱。相反,活病毒在幼龄动物中最常被发现。研究还表明,要从黑线姬鼠成功分离病毒,有必要考虑啮齿动物急性感染的特征:其肺组织中存在HFRS病毒抗原,而血液中缺乏该病毒抗体。

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