Niklasson B, Hornfeldt B, Mullaart M, Settergren B, Tkachenko E, Ryltceva E V, Leschinskaya E, Malkin A, Dzagurova T
Department of Virology, Karoliniska Institute, Stockholm, Sweden.
Am J Trop Med Hyg. 1993 May;48(5):670-5. doi: 10.4269/ajtmh.1993.48.670.
The incidence and antibody prevalence of hemorrhagic fever with renal syndrome (HFRS) in Bashkirtostan (European part of Russia) and northern Sweden was compared with the abundance of Clethrionomys glareolus (bank voles) in the two areas. In Bashkirtostan, 10% of the women and 15% of the men were found to be antibody positive. The corresponding figures for Sweden were 8% and 16% for women and men, respectively. The annual incidence of HFRS in Bashkirtostan was 50 cases per 100,000 inhabitants, with a male:female ratio of 4.6:1. The incidence in the endemic area of Sweden was seven cases per 100,000 inhabitants, with a male:female ratio of 1.8:1. A similar age distribution of cases, with a peak in the middle age groups, especially in men, was found in both Bashkirtostan and Sweden. The incidence of HFRS in humans and the abundance of bank voles varied with time in both Bashkirtostan and Sweden, but the study failed to find any significant correlation between the two variables. The study showed that HFRS causes significant human morbidity in the areas studied but that both incidence and possibly bank vole abundance was higher in Bashkirtostan than in northern Sweden.
对俄罗斯欧洲部分的巴什基尔斯坦和瑞典北部肾综合征出血热（HFRS）的发病率及抗体流行情况，与这两个地区黄毛鼠（田鼠）的数量进行了比较。在巴什基尔斯坦，发现10%的女性和15%的男性抗体呈阳性。瑞典女性和男性的相应数字分别为8%和16%。巴什基尔斯坦HFRS的年发病率为每10万居民50例，男女比例为4.6:1。瑞典流行地区的发病率为每10万居民7例，男女比例为1.8:1。在巴什基尔斯坦和瑞典都发现病例的年龄分布相似，中年组出现高峰，尤其是男性。在巴什基尔斯坦和瑞典，HFRS在人类中的发病率以及田鼠的数量均随时间变化，但该研究未能发现这两个变量之间存在任何显著相关性。研究表明，HFRS在研究地区导致了显著的人类发病，但巴什基尔斯坦的发病率以及可能的田鼠数量均高于瑞典北部。
