小鸡喂食试验：一种检测雪卡毒素的简单系统。
Chick feeding test: a simple system to detect ciguatoxin.
作者信息
Vernoux J P, Lahlou N, Magras L P, Greaux J B
出版信息
Acta Trop. 1985 Sep;42(3):235-40.
PMID:2865879
Abstract
Chick poisoning induced by oral administration of toxic fish tissues or extracts gave rise to internal hypersalivation, decrease in weight and acute motor ataxia. Detoxification was low and repeated administration therefore led to toxin accumulation. Response of the chicken to liver feeding was roughly quantitative; so liver, which is the most potential toxic tissue, may be used for a preventive screening test in ciguatera-endemic areas.
摘要
经口给予有毒鱼类组织或提取物引起的雏鸡中毒会导致口腔内唾液分泌过多、体重减轻和急性运动性共济失调。解毒能力较低，因此重复给药会导致毒素积累。雏鸡对肝脏喂养的反应大致呈定量关系；因此，肝脏作为最具潜在毒性的组织，可用于雪卡毒素流行地区的预防性筛查试验。
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