Varma K Rajasree, Francis Saji, Sathi P P, Reddy C Saikiran
Senior Resident, Department of Pathology, Government Medical College, Kozhikode, Kerala, India.
Associate Professor, Department of Pathology, Government Medical College, Kozhikode, Kerala, India.
J Clin Diagn Res. 2017 May;11(5):ER01-ER03. doi: 10.7860/JCDR/2017/27129.9802. Epub 2017 May 1.
Serous microcystic adenoma is a rare exocrine tumour of the cystic neoplasm of pancreas seen predominantly in the elderly population. The first patient was a 56-year-old diabetic woman with abdominal pain, constipation and loss of weight since two months. The second patient was a 73-year-old female with complaints of abdominal pain and back pain since one year. The third patient was a 72-year-old diabetic man with complaints of burning sensation in the right lumbar region since two months. Clinical and laboratory examinations were normal. The radiological examinations of the first two patients showed multiloculated cystic lesion in the pancreas and of the third patient was suggestive of islet cell tumour. The histopathological examination of the three patients showed multiple cysts of varying sizes lined by cuboidal epithelium, showing no atypia. All the three patients were diagnosed as serous microcystic adenoma of pancreas. On follow up, all three patients had no recurrence. Serous epithelial neoplasms need to be differentiated from their non-neoplastic counterparts and other neoplastic lesions with cystic changes, in view of the differences in management. Serous microcystic adenomas have excellent prognosis.
浆液性微囊性腺瘤是一种罕见的胰腺囊性肿瘤的外分泌肿瘤，主要见于老年人群。首例患者是一名56岁的糖尿病女性，两个月来出现腹痛、便秘和体重减轻。第二例患者是一名73岁女性，一年来一直主诉腹痛和背痛。第三例患者是一名72岁的糖尿病男性，两个月来主诉右腰区有烧灼感。临床和实验室检查均正常。前两名患者的影像学检查显示胰腺有多房性囊性病变，第三例患者的影像学检查提示胰岛细胞瘤。三名患者的组织病理学检查显示多个大小不一的囊肿，内衬立方上皮，无异型性。所有三名患者均被诊断为胰腺浆液性微囊性腺瘤。随访时，所有三名患者均无复发。鉴于治疗方法的差异，浆液性上皮肿瘤需要与非肿瘤性对应物以及其他有囊性改变的肿瘤性病变相鉴别。浆液性微囊性腺瘤预后良好。
