University Hospitals Birmingham, Birmingham, United Kingdom.
Nutr Clin Pract. 2018 Aug;33(4):515-519. doi: 10.1177/0884533617713955. Epub 2017 Dec 14.
A well-functioning alimentary canal is required for adequate nutrient absorption. Disruption to the upper gastrointestinal tract through surgery can lead to micronutrient malnourishment. Copper deficiency has been noted in up to 10% of those undergoing Roux-en-Y gastric bypass surgery, but sequalae are not frequently reported. The resultant deficiency states can have profound and long-term consequences if not realized early and managed appropriately. Here we present a case of copper deficiency myelopathy, a condition indistinguishable from subacute combined degeneration of the spinal cord, following upper gastrointestinal bypass surgery for gastric ulceration, further complicated by inadequate nutrition.
一个运作良好的消化道是充分吸收营养物质的必要条件。手术对上消化道的破坏可导致微量营养素营养不良。在接受 Roux-en-Y 胃旁路手术的患者中,高达 10%的患者出现铜缺乏,但后遗症并不常见。如果不能早期发现和适当处理,由此产生的缺乏状态可能会产生深远和长期的后果。在这里,我们报告了一例铜缺乏性脊髓病,这是一种与脊髓亚急性联合变性无法区分的疾病,发生在上消化道旁路手术后的胃溃疡,进一步复杂化的是营养不足。