Pascoe Michaela C, Thompson David R, Castle David J, McEvedy Samantha M, Ski Chantal F
Department of Cancer Experience Research, Peter MacCallum Cancer CentreMelbourne, VIC, Australia.
Department of Psychiatry, University of MelbourneMelbourne, VIC, Australia.
Front Psychol. 2017 Jun 13;8:992. doi: 10.3389/fpsyg.2017.00992. eCollection 2017.
Depressive and anxiety symptoms are common amongst individuals with chronic kidney disease and are known to affect quality of life adversely. Psychosocial interventions have been shown to decrease depressive and anxiety symptoms in various chronic diseases, but few studies have examined their efficacy in people with chronic kidney disease and no meta-analysis has been published. Thus, the aim of the present systematic review and meta-analysis was to evaluate the effects of psychosocial interventions on depressive and anxiety symptoms as well as quality of life in individuals diagnosed with chronic kidney disease and/or their carers. In this systematic review and meta-analysis, we included published randomized controlled trials comparing psychosocial interventions versus usual care for impacting depressive and anxiety symptoms and quality of life. Eight studies were included in the systematic review and six of these were subjected to meta-analysis. Psychosocial interventions were associated with a medium effect size for reduction in depressive symptoms and a small effect size for improved quality of life in the in individuals with chronic-kidney-disease and their carers. Some evidence suggested a reduction in anxiety. Psychosocial interventions appear to reduce depressive symptoms and improve quality of life in patients with chronic-kidney-disease and their carers and to have some beneficial impact on anxiety. However, the small number of identified studies indicates a need for further research in this field.
抑郁和焦虑症状在慢性肾脏病患者中很常见，并且已知会对生活质量产生不利影响。心理社会干预已被证明可减轻各种慢性疾病中的抑郁和焦虑症状，但很少有研究考察其对慢性肾脏病患者的疗效，也没有发表过荟萃分析。因此，本系统评价和荟萃分析的目的是评估心理社会干预对被诊断为慢性肾脏病的个体及其照顾者的抑郁和焦虑症状以及生活质量的影响。在本系统评价和荟萃分析中，我们纳入了已发表的随机对照试验，这些试验比较了心理社会干预与常规护理对抑郁和焦虑症状以及生活质量的影响。系统评价纳入了八项研究，其中六项进行了荟萃分析。心理社会干预与慢性肾脏病患者及其照顾者抑郁症状减轻的中等效应量以及生活质量改善的小效应量相关。一些证据表明焦虑有所减轻。心理社会干预似乎能减轻慢性肾脏病患者及其照顾者的抑郁症状，改善生活质量，并对焦虑有一定的有益影响。然而，已确定的研究数量较少，表明该领域需要进一步研究。
