Nadort Els, van Geenen Noëlle J K, Schouten Robbert W, Boeschoten Rosa E, Chandie Shaw Prataap, Vleming Louis Jean, Schouten Marcel, Farhat Karima, Dekker Friedo W, van Oppen Patricia, Siegert Carl E H, Broekman Birit F P
Department of Psychiatry, OLVG Hospital, Jan Tooropstraat 164, 1061 AE Amsterdam, The Netherlands.
Department of Psychiatry, Amsterdam University Medical Centre and GGZ inGeest, Oldenaller 1, 1081 HJ Amsterdam, The Netherlands.
J Pers Med. 2022 Jun 30;12(7):1077. doi: 10.3390/jpm12071077.
Symptoms of anxiety are often unrecognized and untreated in dialysis patients. We investigated the diagnostic accuracy of two widely used screening tools for anxiety in hemodialysis patients.
For this cross-sectional validation study, chronic hemodialysis patients from eight dialysis centers in the Netherlands were included. The Beck Anxiety Inventory (BAI) and Hospital Anxiety and Depression Scale-Anxiety subscale (HADS-A) were validated by the Mini International Neuropsychiatric Inventory (MINI) diagnostic interview. Receiver operating characteristic curves were used to determine the optimal cut-off values.
Of 65 participants, 13 (20%) were diagnosed with one or more anxiety disorders on the MINI, of which 5 were included in the analysis. ROC curves showed a good diagnostic accuracy of the BAI and HADS-A. The optimal cut-off value for the BAI was ≥13 (sensitivity 100%, specificity 85%) and for the HADS-A was ≥10 (sensitivity 80%, specificity 100%).
Based on our limited data, both the BAI and the HADS-A seem to be valid screening instruments for anxiety in hemodialysis patients that can be used in routine dialysis care. The HADS-A consists of fewer items and showed fewer false-positive results than the BAI, which might make it more useful in clinical practice.
透析患者的焦虑症状常常未被识别和治疗。我们研究了两种广泛使用的用于筛查血液透析患者焦虑症的工具的诊断准确性。
对于这项横断面验证研究，纳入了来自荷兰八个透析中心的慢性血液透析患者。贝克焦虑量表（BAI）和医院焦虑抑郁量表焦虑分量表（HADS-A）通过迷你国际神经精神访谈量表（MINI）诊断访谈进行验证。采用受试者工作特征曲线来确定最佳截断值。
65名参与者中，13人（20%）在MINI上被诊断患有一种或多种焦虑症，其中5人纳入分析。ROC曲线显示BAI和HADS-A具有良好的诊断准确性。BAI的最佳截断值为≥13（敏感性100%，特异性85%），HADS-A的最佳截断值为≥10（敏感性80%，特异性100%）。
基于我们有限的数据，BAI和HADS-A似乎都是用于血液透析患者焦虑症的有效筛查工具，可用于常规透析护理。HADS-A项目较少，假阳性结果比BAI少，这可能使其在临床实践中更有用。
