Nahata Leena, Chelvakumar Gayathri, Leibowitz Scott
1 The Ohio State University/Nationwide Children's Hospital, Columbus, OH, USA.
2 Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Ann Pharmacother. 2017 Nov;51(11):1023-1032. doi: 10.1177/1060028017718845. Epub 2017 Jun 29.
Youth with gender dysphoria, also known as transgender youth, are increasingly presenting to multidisciplinary clinics within academic pediatric centers across the United States. Gender-affirming pharmacological interventions for adolescents with gender dysphoria may be used to promote positive psychological well-being and mental health outcomes. Interventions range from completely reversible to partially irreversible, based on the age and sexual maturity of the adolescent. For each intervention, dilemmas and controversies exist regarding age at treatment initiation, treatment duration, safety, and cost. Pharmacists' awareness of these considerations and interventions is important when providing evidence-based gender-affirming care to this underserved population.
患有性别焦虑症的青少年，也被称为跨性别青少年，越来越多地前往美国各地学术性儿科中心的多学科诊所就诊。对患有性别焦虑症的青少年进行性别肯定的药物干预，可用于促进积极的心理健康和精神健康结果。根据青少年的年龄和性成熟程度，干预措施从完全可逆到部分不可逆不等。对于每一种干预措施，在治疗开始的年龄、治疗持续时间、安全性和成本方面都存在困境和争议。当为这一服务不足的人群提供基于证据的性别肯定护理时，药剂师对这些考虑因素和干预措施的了解很重要。
