FAAD-FEADV Medical and Scientific Director, SDC The Skin Doctors Center, Trieste, Italy.
J Eur Acad Dermatol Venereol. 2018 Jan;32(1):113-116. doi: 10.1111/jdv.14446. Epub 2017 Aug 4.
Aesthetically pleasing results and fast, uneventful recovery are highly desirable after rejuvenating ablative laser procedures. Wound dressings following ablative laser procedures should ideally improve and optimize the wound healing environment.
The purpose of this comparative split-face, single-blinded, prospective observational study was to assess the efficacy and acceptability of two primary wound dressings immediately after a full-face fractional CO laser resurfacing procedure.
The assessments of an innovative film-forming dressing called Stratacel (SC) vs spring thermal water + Vaseline (V+) were conducted after a standardized, single-pass, full-face ablative fractional CO laser skin resurfacing procedure. Clinical parameters, such as haemoglobin - HB; surface temperature - ST; micro-textural modifications - MT; superficial melanin - M; intrafollicular porphyrins - P, were assessed at different phases of the healing process using standardized, non-invasive technologies.
Five female volunteers were enrolled in this inpatient, controlled pilot study. Most of the clinical parameters considered, including 3D surface texture analysis, revealed a better performance of SC vs. V+ during the early, more delicate phases of the healing process.
This preliminary study, even if performed on a small number of volunteers, confirmed a definite advantage of the tested semipermeable film-forming formula (SC) over a more conventional postoperative skin care regime (V+). Clinical results could be explained by a better uniformity of distribution of SC over the micro-irregularities induced by ablative fractional CO laser resurfacing. Its thin, semipermeable film might, in fact, act as an efficient, perfectly biocompatible, full contact, temporary skin barrier, able to protect extremely delicate healing surfaces from potential environmental irritations.
在进行焕肤激光美容后，人们希望能获得令人满意的美学效果，同时能快速且无意外地恢复。理想情况下，激光美容术后的伤口敷料应改善和优化伤口愈合环境。
本项对比性、半脸、单盲、前瞻性观察研究旨在评估一种新型的薄膜创面敷料（Stratacel，SC）与 spring 温泉水+凡士林（V+）在全脸分段式 CO2 激光换肤术后即刻的疗效和可接受性。
在标准化单次全脸消融性分段式 CO2 激光皮肤换肤术后，对新型薄膜创面敷料 Stratacel（SC）与 spring 温泉水+凡士林（V+）进行评估。使用标准化的非侵入性技术在不同的愈合阶段评估血红蛋白（HB）、表面温度（ST）、微观纹理改变（MT）、浅表黑色素（M）和毛囊内卟啉（P）等临床参数。
本住院控制先导研究纳入 5 名女性志愿者。考虑到的大多数临床参数，包括 3D 表面纹理分析，均显示在愈合过程的早期更精细阶段，SC 相对于 V+具有更好的性能。
即使在少数志愿者中进行，这项初步研究也证实了经过测试的半渗透性成膜配方（SC）相对于更传统的术后皮肤护理方案（V+）具有明显优势。临床结果可以通过 SC 在更均匀地分布于由消融性分段式 CO2 激光换肤术引起的微不规则性上得到解释。其薄而半渗透性的薄膜实际上可以作为一种有效的、完全生物相容的、完全接触的临时皮肤屏障，能够保护极其脆弱的愈合表面免受潜在环境刺激。
