Mahajan Rajiv, Pathak Rajeev K, Thiyagarajah Anand, Lau Dennis H, Marchlinski Francis E, Dixit Sanjay, Day John D, Hendriks Jeroen M L, Carrington Melinda, Kalman Jonathan M, Sanders Prashanthan
Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, SA, Australia.
Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, SA, Australia; Cardiac Electrophysiology Section, Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Heart Lung Circ. 2017 Sep;26(9):990-997. doi: 10.1016/j.hlc.2017.05.123. Epub 2017 Jun 9.
Atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality worldwide. Management of AF is a complex process involving: 1) the prevention of thromboembolic complications with anticoagulation; 2) rhythm control; and 3) the detection and treatment of underlying heart disease. However, cardiometabolic risk factors, such as obesity, hypertension, diabetes mellitus, and obstructive sleep apnoea, have been proposed as contributors to the expanding epidemic of atrial fibrillation (AF). Thus, a fourth pillar of AF care would include aggressive targeting of interdependent, modifiable cardiovascular risk factors as part of an integrated care model. Such risk factor management could retard and reverse the pathological processes underlying AF and reduce AF burden.
心房颤动（AF）是全球心血管疾病发病和死亡的主要原因。房颤的管理是一个复杂的过程，包括：1）通过抗凝预防血栓栓塞并发症；2）节律控制；3）潜在心脏病的检测和治疗。然而，肥胖、高血压、糖尿病和阻塞性睡眠呼吸暂停等心脏代谢危险因素已被认为是导致心房颤动（AF）流行趋势扩大的因素。因此，房颤护理的第四大支柱将包括在综合护理模式中积极针对相互关联、可改变的心血管危险因素。这种危险因素管理可以延缓和逆转房颤潜在的病理过程，减轻房颤负担。
