Franzen Daniel, Schneiter Didier, Weder Walter, Kohler Malcolm
Division of Pulmonology, University Hospital Zurich, Raemistrasse, Zurich, Switzerland.
Division of Thoracic Surgery, University Hospital Zurich, Raemistrasse, Zurich, Switzerland.
Endosc Ultrasound. 2017 Jul-Aug;6(4):257-263. doi: 10.4103/2303-9027.190925.
There is a paucity of data concerning the impact of the sedation technique used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on diagnostic accuracy. The aim of this retrospective study was to compare the diagnostic accuracy of EBUS-TBNA in deep and moderate sedations, and to investigate other possible determinants of diagnostic accuracy in three lymph node locations (mediastinal, subcarinal, and hilar).
The first consecutive patients at our institution undergoing EBUS-TBNA for selective sampling in deep sedation were compared with the first consecutive patients in moderate sedation between 2006 and 2014. Diagnoses based on EBUS-TBNA were compared with those on surgical or radiological follow-up.
In a total of 232 patients, the overall diagnostic accuracy for correct diagnosis at the mediastinal, subcarinal, and hilar locations irrespective of the sedation technique was 91%, 93%, and 92%, respectively. At the three mentioned lymph node locations, overall diagnostic accuracy of EBUS-TBNA in deep sedation compared to moderate sedation was 88.5% and 95.5% (P = 0.3), 93.2 and 93.6% (P = 0.9), and 88.6 and 94.0% (P = 0.4), respectively.
The sedation technique does not seem to influence the diagnostic accuracy of EBUS-TBNA.
关于用于支气管内超声引导经支气管针吸活检术（EBUS-TBNA）的镇静技术对诊断准确性影响的数据较少。这项回顾性研究的目的是比较深度镇静和中度镇静下EBUS-TBNA的诊断准确性，并调查在三个淋巴结部位（纵隔、隆突下和肺门）诊断准确性的其他可能决定因素。
将2006年至2014年间在我院接受EBUS-TBNA进行深度镇静下选择性采样的首批连续患者与首批连续接受中度镇静的患者进行比较。将基于EBUS-TBNA的诊断与手术或放射学随访的诊断进行比较。
在总共232例患者中，无论镇静技术如何，在纵隔、隆突下和肺门部位正确诊断的总体诊断准确性分别为91%、93%和92%。在上述三个淋巴结部位，深度镇静与中度镇静相比，EBUS-TBNA的总体诊断准确性分别为88.5%和95.5%（P = 0.3）、93.2%和93.6%（P = 0.9）、88.6%和94.0%（P = 0.4）。
镇静技术似乎不影响EBUS-TBNA的诊断准确性。
Zotero 插件