Miller Sarah, Walls Tony, Atkinson Neil, Zaleta Sona
Timaru Hospital, South Canterbury, New Zealand 7190.
Christchurch Hospital, Riccarton Avenue, Christchurch, New Zealand.
JMM Case Rep. 2014 Dec 1;1(4):e004408. doi: 10.1099/jmmcr.0.004408. eCollection 2014 Dec.
Actinomycosis is a granulomatous suppurative infection caused by filamentous Gram-positive anaerobic bacteria from the family . To our knowledge, this is the first reported case of otogenic brain abscess associated with .
We report the case of an immunocompetent 5-year-old boy with recurrent otitis media who re-presented to the emergency department with a 3-week history of otorrhoea, progressive anorexia, vomiting and lethargy. He was admitted with a working diagnosis of otitis media and dehydration, and was treated with intravenous fluids and oral co-trimoxazole. He subsequently developed abnormal posturing with a reduced Glasgow coma score and seizures. Urgent computed tomography revealed a cerebellar abscess with obstructive hydrocephalus for which he underwent urgent neurosurgical intervention. Tissue and aspirate cultures revealed a polymicrobial infection with . The patient has since undergone long-term antibiotic treatment and has made a good recovery.
This case demonstrates the successful use of long-term antibiotic therapy and neurosurgical intervention to treat otogenic brain abscess associated with infection. To the best of our knowledge, this is the first such documented case. Our report also provides a timely reminder that, despite a reduced incidence in the developed world, intracranial complications of otitis media continue to occur and a high index of suspicion is required.
放线菌病是由放线菌科的丝状革兰氏阳性厌氧菌引起的肉芽肿性化脓性感染。据我们所知,这是首例报道的与[此处原文缺失相关内容]相关的耳源性脑脓肿病例。
我们报告一例免疫功能正常的5岁男孩,有复发性中耳炎病史,因耳漏、进行性厌食、呕吐和嗜睡3周再次就诊于急诊科。他因中耳炎和脱水的初步诊断入院,接受了静脉补液和口服复方新诺明治疗。随后他出现异常姿势,格拉斯哥昏迷评分降低并伴有癫痫发作。紧急计算机断层扫描显示小脑脓肿伴梗阻性脑积水,为此他接受了紧急神经外科干预。组织和抽吸物培养显示为[此处原文缺失相关内容]的混合感染。此后,该患者接受了长期抗生素治疗,恢复良好。
本病例表明,长期抗生素治疗和神经外科干预成功用于治疗与[此处原文缺失相关内容]感染相关的耳源性脑脓肿。据我们所知,这是首例有记录的此类病例。我们的报告还及时提醒,尽管在发达国家发病率有所降低,但中耳炎的颅内并发症仍会发生,需要高度怀疑。