Li Ying, Zhu Ling, Yang Wei, You Chengdong
Department of Infectious Diseases, People's Hospital of Xiushan County, Chongqing, China.
Front Med (Lausanne). 2025 Aug 8;12:1626567. doi: 10.3389/fmed.2025.1626567. eCollection 2025.
This CARE-guided report details a rare case of bloodstream infection caused by coinfection of and in a 69-year-old male with diabetic foot. and are an opportunistic pathogen that rarely causes human infection, while bloodstream infection is more rarely. They are tend to occur in immunocompromised individuals and are highly susceptible to mixed infections with other opportunistic pathogens. can cause invasive infections, including bloodstream infection, abscess, endocarditis and other infectious diseases. We reported a 69-year-old male with type 2 diabetes mellitus complicated by a chronic, neuropathic, right-first-toe ulcer (Wagner grade 4 with underlying osteomyelitis), presented with chills, fever, and foot pain. Cultures of blood and purulent secretions from the foot revealed a mixed infection that was predominantly caused by and . After 9 days of treatment with antibiotics, the patient exhibited a satisfactory recovery and he was discharged from the hospital. Clinicians should pay attention to disseminated infections caused by and . Timely microbiological examinations and accurate identification methods are conducive to early diagnosis. The prognosis is relatively favorable with appropriate antibiotics, lesion removal, and other therapeutic measures.
这份基于CARE指南的报告详细描述了一例罕见的血流感染病例，该病例发生在一名69岁患有糖尿病足的男性身上，由[两种病原体名称未给出]合并感染引起。[两种病原体名称未给出]是一种机会性病原体，很少引起人类感染，而血流感染则更为罕见。它们往往发生在免疫功能低下的个体中，并且极易与其他机会性病原体发生混合感染。[两种病原体名称未给出]可引起侵袭性感染，包括血流感染、脓肿、心内膜炎及其他传染病。我们报告了一名69岁的2型糖尿病男性患者，其患有慢性神经性右拇趾溃疡（Wagner 4级并伴有潜在骨髓炎），出现寒战、发热和足部疼痛。血液及足部脓性分泌物培养显示为主要由[两种病原体名称未给出]引起的混合感染。经过9天的抗生素治疗，患者恢复良好并出院。临床医生应关注由[两种病原体名称未给出]引起的播散性感染。及时进行微生物学检查和准确的鉴定方法有助于早期诊断。通过适当的抗生素、病灶清除及其他治疗措施，预后相对良好。
