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中耳放线菌病酷似胆脂瘤:一例报告及文献复习

Actinomycosis of the Middle Ear Mimicking Cholesteatoma: A Case Report and Literature Review.

作者信息

Modi Shagoon, Kiverniti Eleftheria

机构信息

Surgery, Princess Alexandra Hospital, Harlow, GBR.

Otolaryngology, Princess Alexandra Hospital, Harlow, GBR.

出版信息

Cureus. 2024 Feb 27;16(2):e55014. doi: 10.7759/cureus.55014. eCollection 2024 Feb.

Abstract

Actinomycosis is a rare infection of the middle ear. Actinomyces is an anaerobic, filamentous bacterium causing granuloma formation and suppurative infection. We present a young male with a nine-month history of unilateral, yellow-coloured otorrhoea and hearing loss. Swabs showed no growth, with the infection not responding to oral or topical antibiotics. Computed tomography of temporal bones was consistent with cholesteatoma and ossicular disruption. Surgical exploration revealed a yellow, cystic mass within the middle ear. Cortical mastoidectomy and washout were performed. Histological diagnosis confirmed Actinomyces clusters with positive gram stain. Actinomycosis of the middle ear typically presents as chronic otitis media. It likely reaches the middle ear via the eustachian tube. It is often misdiagnosed due to culture insensitivity; however, clinical suspicion can aid labs in providing an optimum culture environment. Tympanomastoidectomy allows for histopathological diagnosis. Surgical resection should be followed by a prolonged course of antibiotics.

摘要

放线菌病是一种罕见的中耳感染。放线菌是一种厌氧的丝状细菌,可导致肉芽肿形成和化脓性感染。我们报告一名年轻男性,有9个月单侧黄色耳漏和听力损失的病史。拭子培养无细菌生长,感染对口服或局部抗生素均无反应。颞骨计算机断层扫描结果与胆脂瘤和听骨链破坏一致。手术探查发现中耳内有一个黄色囊性肿物。进行了皮质乳突切除术和冲洗。组织学诊断证实为革兰氏染色阳性的放线菌簇。中耳放线菌病通常表现为慢性中耳炎。它可能通过咽鼓管到达中耳。由于培养不敏感,该病常被误诊;然而,临床怀疑有助于实验室提供最佳培养环境。鼓室乳突切除术可实现组织病理学诊断。手术切除后应使用较长疗程的抗生素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a904/10897636/f29b59bd7544/cureus-0016-00000055014-i01.jpg

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