Departamento de Química Orgánica, Universidad de Murcia , Campus de Espinardo, E-30100 Murcia, Spain.
Chem Rev. 2017 Aug 9;117(15):9907-9972. doi: 10.1021/acs.chemrev.6b00814. Epub 2017 Jun 30.
This review highlights the most significant examples of an emerging field in the design of highly selective anion receptors. To date, there has been remarkable progress in the binding and sensing of anions. This has been driven in part by the discovery of ways to construct effective anion binding receptors using the dominant N-H functional groups and neutral and cationic C-H hydrogen bond donors, as well as underexplored strong directional noncovalent interactions such as halogen-bonding and anion-π interactions. In this review, we will describe a new and promising strategy for constructing anion binding receptors with distinct advantages arising from their elaborate design, incorporating multiple binding sites able to interact cooperatively with anions through these different kinds of noncovalent interactions. Comparisons with control species or solely hydrogen-bonding analogues reveal unique characteristics in terms of strength, selectivity, and interaction geometry, representing important advances in the rising field of supramolecular chemistry.
这篇综述重点介绍了设计高选择性阴离子受体这一新兴领域中最具代表性的例子。迄今为止，阴离子的结合和传感方面已经取得了显著的进展。这部分是由于发现了使用主导的 N-H 官能团和中性及阳离子 C-H 氢键供体构建有效阴离子结合受体的方法，以及利用尚未充分探索的强定向非共价相互作用（如卤键和阴离子-π 相互作用）的方法。在这篇综述中，我们将描述一种新的、有前途的策略，用于构建阴离子结合受体，这些受体具有独特的优势，源于其精心设计，包含多个结合位点，能够通过这些不同类型的非共价相互作用与阴离子协同相互作用。与对照物或仅氢键类似物的比较揭示了在强度、选择性和相互作用几何形状方面的独特特征，代表了超分子化学这一新兴领域的重要进展。
