Gosney J R, Sissons M C, O'Malley J A
Thorax. 1985 Nov;40(11):866-9. doi: 10.1136/thx.40.11.866.
There was no significant variation in the numbers of bronchopulmonary endocrine cells immunoreactive for calcitonin in five pairs of adult human lungs either from case to case or between groups of anatomically equivalent lobes. This was the case whether their numbers were expressed in relation to epithelial length or to the total number of epithelial cells. The mean (SD) values for the frequency of occurrence of these cells in all 25 lobes studied were 4.3 (1.9) per 10 cm of epithelial length or 1.70 (0.78) per 10 000 epithelial cells. Most immunoreactive cells were single and situated in the airways; only three neuroepithelial bodies were observed, and no cells were present in the parenchyma examined. This study provides further evidence that the functional character of these cells may not be confined to early life.
在五对成年人类肺脏中，降钙素免疫反应性支气管肺内分泌细胞的数量，无论是在个体之间还是在解剖学上相对应的肺叶组之间，均无显著差异。无论这些细胞的数量是相对于上皮长度还是相对于上皮细胞总数来表示，情况都是如此。在所有25个研究肺叶中，这些细胞出现频率的平均值（标准差）为每10厘米上皮长度4.3（1.9）个，或每10000个上皮细胞1.70（0.78）个。大多数免疫反应性细胞是单个的，位于气道中；仅观察到三个神经上皮小体，在所检查的实质中未发现细胞。这项研究进一步证明，这些细胞的功能特性可能不限于生命早期。
