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法属圭亚那的终末期肾病(来自R.E.I.N登记处的数据):南美特征还是法国特征?

End stage renal disease in French Guiana (data from R.E.I.N registry): South American or French?

作者信息

Rochemont Dévi Rita, Meddeb Mohamed, Roura Raoul, Couchoud Cécile, Nacher Mathieu, Basurko Célia

机构信息

Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane CIC INSERM 1424, Centre hospitalier Andrée Rosemon, Rue des flamboyants BP 6006, 97306, Cayenne, French Guiana.

KAPA santé, Clinique Véronique, 1453 rte Baduel, 97300, Cayenne, French Guiana.

出版信息

BMC Nephrol. 2017 Jun 30;18(1):207. doi: 10.1186/s12882-017-0614-6.

Abstract

BACKGROUND

End-Stage renal disease (ESRD) causes considerable morbidity and mortality, and significantly alters patients' quality of life. There are very few published data on this problem in the French Overseas territories. The development of a registry on end stage renal disease in French Guiana in 2011 allowed to describe the magnitude of this problem in the region for the first time.

METHODS

Using data from the French Renal Epidemiology and Information Network registry (R.E.I.N). Descriptive statistics on quantitative and qualitative variables in the registry were performed on prevalent cases and incident cases in 2011, 2012 and 2013.

RESULTS

French Guiana has one of the highest ESRD prevalence and incidence in France. The two main causes of ESRD were hypertensive and diabetic nephropathies. The French Guianese population had a different demographic profile (younger, more women, more migrants) than in mainland France. Most patients had at least one comorbidity, predominantly (95.3%) hypertension. In French Guiana dialysis was initiated in emergency for 71.3% of patients versus 33% in France (p < 0.001).

CONCLUSION

These first results give important public health information: i) End stage renal disease has a very high prevalence relative to mainland France ii) Patients have a different demographic profile and enter care late in the course of their renal disease. These data are closer to what is observed in the Caribbean or in Latin America than in Mainland France.

摘要

背景

终末期肾病(ESRD)会导致相当高的发病率和死亡率,并显著改变患者的生活质量。在法属海外领地,关于这个问题的已发表数据非常少。2011年法属圭亚那建立了终末期肾病登记处,这使得首次能够描述该地区这一问题的严重程度。

方法

使用法国肾脏流行病学和信息网络登记处(R.E.I.N)的数据。对登记处中定量和定性变量的描述性统计是针对2011年、2012年和2013年的现患病例和新发病例进行的。

结果

法属圭亚那的ESRD患病率和发病率在法国是最高的之一。ESRD的两个主要病因是高血压性和糖尿病性肾病。法属圭亚那的人口统计学特征与法国本土不同(更年轻、女性更多、移民更多)。大多数患者至少有一种合并症,主要是(95.3%)高血压。在法属圭亚那,71.3%的患者在紧急情况下开始透析,而在法国这一比例为33%(p < 0.001)。

结论

这些初步结果提供了重要的公共卫生信息:i)相对于法国本土,终末期肾病的患病率非常高;ii)患者的人口统计学特征不同,并且在肾病病程后期才开始接受治疗。这些数据更接近在加勒比地区或拉丁美洲观察到的情况,而不是法国本土。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c799/5493068/72770b49f791/12882_2017_614_Fig1_HTML.jpg

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