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经皮神经电刺激(TNS)、电针(EA)与哌替啶治疗术后疼痛的镇痛效果比较研究

Comparative study of the analgesic effect of transcutaneous nerve stimulation (TNS); electroacupuncture (EA) and meperidine in the treatment of postoperative pain.

作者信息

Martelete M, Fiori A M

出版信息

Acupunct Electrother Res. 1985;10(3):183-93. doi: 10.3727/036012985816714432.

DOI:10.3727/036012985816714432
PMID:2866672
Abstract

Seventy two patients, from 15 to 60 years old, in good physical status and submitted to surgery in the upper or lower abdominal, rectal or lumbar areas were studied. In the immediate postoperative period, they were randomly divided in three groups and each group was submitted to one of the following treatments: intravenous meperidine, transcutaneous nerve stimulation (TNS) or electroacupuncture (EA). Each treatment was divided in two phases with one hour interval between them. Each phase was constituted of 30 minutes of stimulation in case of TNS and EA and fractionated administration of meperidine in all groups. The pain level was evaluated through a visual analogue scale before and after each phase of treatment. The results were compared among groups and, on each group, between the phases of treatment. In all surgery types, the postoperative pain relief presented by TNS and EA groups of patients was greater than that of meperidine treated group. But, the analgesia presented by the EA treated group of patients lasted longer and increased with the repetition of treatment. The differences of behaviour of TNS and EA analgesia suggest that their neurochemical mechanisms may not be the same.

摘要

研究对象为72例年龄在15至60岁之间、身体状况良好且接受上腹部或下腹部、直肠或腰部手术的患者。在术后即刻,他们被随机分为三组,每组接受以下一种治疗:静脉注射哌替啶、经皮神经电刺激(TNS)或电针(EA)。每种治疗分为两个阶段,两阶段之间间隔一小时。在TNS和EA治疗中,每个阶段为30分钟的刺激,所有组均采用哌替啶分次给药。在每个治疗阶段前后,通过视觉模拟评分法评估疼痛程度。对组间结果以及每组治疗阶段间的结果进行比较。在所有手术类型中,TNS组和EA组患者术后的疼痛缓解程度均大于哌替啶治疗组。但是,EA治疗组患者的镇痛效果持续时间更长,且随着治疗的重复而增强。TNS和EA镇痛行为的差异表明它们的神经化学机制可能不同。

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