Trushinskaya G N, Ivanova V T, Russ G, Poláková K, Isachenko V A, Zakstelskaya L A
Acta Virol. 1985 Sep;29(5):428-31.
Influenza A and B viruses isolated from animals and man were studied by solid phase radioimmunoassay (SP RIA) using monoclonal antibodies to the A/Dunedin/4/73 strain nucleoprotein (NP). Only influenza A viruses isolated before 1980 interacted with the monoclonal antibody set used, while strains isolated between 1980 and 1983 failed to do so. It was shown that RIA employing monoclonal antibodies was useful for rapid identification of influenza virus NP in the allantoic fluid containing fresh influenza A virus isolates.
利用针对A/达尼丁/4/73株核蛋白（NP）的单克隆抗体，通过固相放射免疫测定法（SP RIA）对从动物和人类中分离出的甲型和乙型流感病毒进行了研究。只有1980年以前分离出的甲型流感病毒与所用的单克隆抗体组发生相互作用，而1980年至1983年间分离出的毒株则没有。结果表明，采用单克隆抗体的放射免疫测定法可用于快速鉴定含有新鲜甲型流感病毒分离株的尿囊液中的流感病毒NP。
