IGenomix, Valencia, Spain.
IVI Madrid, Rey Juan Carlos University, IdiPAZ, Madrid, Spain.
Fertil Steril. 2017 Jul;108(1):28-31. doi: 10.1016/j.fertnstert.2017.06.002.
Many women with endometriosis experience compromised fertility. This disease clearly exerts quantitative damage on the ovaries, and perhaps, also qualitative damage. However, it remains controversial whether endometrial receptivity is compromised. Here we review the evidence from basic transcriptomic signature data to clinical data from an oocyte donation model and find support for the concept that endometrial receptivity is not impaired in women with endometriosis when healthy embryos reach the endometrial cavity.
许多患有子宫内膜异位症的女性生育能力受损。这种疾病显然对卵巢造成了数量上的损害，也许还有质量上的损害。然而，子宫内膜容受性是否受损仍存在争议。在这里，我们回顾了从基础转录组特征数据到卵母细胞捐赠模型的临床数据的证据，发现当健康胚胎到达子宫内膜腔时，子宫内膜容受性在患有子宫内膜异位症的女性中没有受损的这一概念得到了支持。
