Division of Neurosciences, Instituto Nacional de Rehabilitación, Mexico City, Mexico.
Research Laboratories and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genova, Italy.
Semin Arthritis Rheum. 2017 Dec;47(3):432-444. doi: 10.1016/j.semarthrit.2017.06.001. Epub 2017 Jun 28.
To provide an overview of the main nailfold capillaroscopy (NFC) changes described in dermatomyositis (DM) and polymyositis (PM) and to discuss the current evidence supporting its clinical relevance and applications in daily practice.
All relevant literature in the field of NFC and DM and PM published in the last 30 years has been systematically reviewed. A systematic research was performed in the electronic databases PubMed and EMBASE.
A total of 540 publications were identified according to the proposed filters and 27 were included for the review. The articles have been critically analyzed with a focus on technical aspects, examined anatomical areas, main pathological capillaroscopy findings ,and the relationship between NFC alterations and critical parameters of DM and PM.
The overview confirms that NFC is a safe and noninvasive tool able to help the clinician in the diagnosis of DM and PM and to better characterize the phase of disease activity of these patients.
概述皮肌炎（DM）和多发性肌炎（PM）中描述的主要甲襞毛细血管显微镜检查（NFC）变化，并讨论支持其临床相关性及其在日常实践中应用的当前证据。
系统地回顾了过去 30 年来 NFC 和 DM 及 PM 领域的所有相关文献。在电子数据库 PubMed 和 EMBASE 中进行了系统研究。
根据提出的筛选标准，共确定了 540 篇出版物，其中有 27 篇被纳入审查。文章从技术方面、检查的解剖区域、主要的毛细血管镜下发现以及 NFC 改变与 DM 和 PM 的关键参数之间的关系等方面进行了批判性分析。
综述证实 NFC 是一种安全、非侵入性的工具，能够帮助临床医生诊断 DM 和 PM，并更好地描述这些患者疾病活动期的特征。
