Rivière J L, Grolleau G, Bach J
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;82(2):439-43. doi: 10.1016/0742-8413(85)90189-6.
Hepatic biotransformation was studied in microsomal (cytochrome P-450-dependent monooxygenase activities) and cytosolic (glutathione S-transferase activities) fractions from Japanese quail (Coturnix coturnix) and buzzard (Buteo buteo). Monooxygenase activities were not very different apart from a high 7-ethoxycoumarin de-ethylase activity in quail as compared to buzzard. Glutathione S-transferase activities were higher in quail than in buzzard. DP5 (a commercial mixture of PCBs containing 50% chlorine) produced a marked increase in monooxygenase activity from quail liver. In contrast, no induction was found in buzzard under the same conditions. Glutathione S-transferase activities were not modified in both species.
对鹌鹑（日本鹌鹑，Coturnix coturnix）和秃鹫（Buteo buteo）的微粒体（细胞色素P-450依赖性单加氧酶活性）和胞质溶胶（谷胱甘肽S-转移酶活性）部分的肝脏生物转化进行了研究。除了鹌鹑中7-乙氧基香豆素脱乙基酶活性高于秃鹫外，单加氧酶活性差异不大。鹌鹑中的谷胱甘肽S-转移酶活性高于秃鹫。DP5（一种含50%氯的多氯联苯商业混合物）使鹌鹑肝脏中的单加氧酶活性显著增加。相比之下，在相同条件下秃鹫未发现诱导现象。两种物种的谷胱甘肽S-转移酶活性均未改变。
