Riviere J L, De Lavaur E, Grolleau G
Toxicology. 1978 Dec;11(4):329-34. doi: 10.1016/s0300-483x(78)91989-3.
PCB (DP5, 1 and 5 mg/female/day, orally for 40 days) induce microsomal hepatic enzymes (cytochrome P-450, aniline hydroxylase, aldrin epoxidase, p-nitroanisole demethylase, p-nitrophenol: UDPGA-transferase) in adult female Japanese quail. Toxicity of dinitro-o-cresol (DNOC) is reduced in treated animals. High hepatic activity occurs in young quails issued from treated females, but closely related to residue levels, normal enzyme activities are reestablished within 1 month.
