Tate S S
FEBS Lett. 1986 Jan 1;194(1):33-8. doi: 10.1016/0014-5793(86)80046-1.
The two subunits of gamma-glutamyl transpeptidase (EC 2.3.2.2) are derived from a single-chain glycosylated precursor. A small fraction of the propeptide survives proteolytic processing in the rat kidney and has been purified by an immunoaffinity technique. The propeptide contains determinants for both the subunits and its amino acid composition resembles that of the dimeric enzyme. However, the propeptide exhibits less than 2% of the transpeptidase activity shown by the dimeric enzyme.
γ-谷氨酰转肽酶（EC 2.3.2.2）的两个亚基来源于一条单链糖基化前体。在大鼠肾脏中，一小部分前肽在蛋白水解加工过程中留存下来，并已通过免疫亲和技术进行了纯化。该前肽包含两个亚基的决定簇，其氨基酸组成与二聚体酶相似。然而，该前肽的转肽酶活性不到二聚体酶的2%。
