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动态稳定化术后椎间盘再水化:59例报告

Disc Rehydration after Dynamic Stabilization: A Report of 59 Cases.

作者信息

Yilmaz Atilla, Senturk Salim, Sasani Mehdi, Oktenoglu Tunc, Yaman Onur, Yildirim Hakan, Suzer Tuncer, Ozer Ali Fahir

机构信息

Department of Neurosurgery, Mustafa Kemal University, Hatay, Turkey.

Department of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey.

出版信息

Asian Spine J. 2017 Jun;11(3):348-355. doi: 10.4184/asj.2017.11.3.348. Epub 2017 Jun 15.

Abstract

STUDY DESIGN

A retrospective study investigating decrease in the nucleus pulposus signal intensity or disc height on magnetic resonance imaging (MRI) and disc degeneration.

PURPOSE

Although a degenerated disc cannot self-regenerate, distraction or stabilization may provide suitable conditions for rehydration and possible regeneration. This study aimed to evaluate clinical outcomes and disc regeneration via MRI in a series of patients with degenerative disc disease (DDD) who underwent lumbar stabilization with a dynamic stabilization system (DSS).

OVERVIEW OF LITERATURE

A dynamic system provides rehydration during early DDD.

METHODS

Fifty-nine patients (mean age, 46.5 years) who undedwent stabilization with DSS for segmental instability (painful black disc) between 2004 and 2014 were retrospectively evaluated. All patients underwent MRI preoperatively and 12 months postoperatively. Intervertebral disc (IVD) degeneration grades at the implanted segment were categorized using the Pfirrmann classification system. Patients were followed for a mean of 6.4 years, and clinical outcomes were based on visual analog scale (VAS) and Oswestry disability index (ODI) scores.

RESULTS

Significant improvements in back pain VAS and ODI scores from before surgery (7 and 68%, respectively) were reported at 6 (2.85 and 27.4%, respectively) and 12 months postoperatively (1.8 and 16.3%, respectively). Postoperative IVD changes were observed in 28 patients. Improvement was observed in 20 patients (34%), whereas progressive degeneration was observed in eight patients (13.5%). Thirty-one patients (52.5%) exhibited neither improvement nor progression. Single Pfirrmann grade improvements were observed in 29% of the patients and two-grade improvements were observed in 5%.

CONCLUSIONS

Our observations support the theory that physiological movement and a balanced load distribution are necessary for disc regeneration. We conclude that DSS may decelerate the degeneration process and appears to facilitate regeneration.

摘要

研究设计

一项回顾性研究,调查磁共振成像(MRI)上髓核信号强度降低或椎间盘高度以及椎间盘退变情况。

目的

尽管退变的椎间盘无法自我再生,但撑开或稳定化可能为再水化及可能的再生提供适宜条件。本研究旨在通过MRI评估一系列接受动态稳定系统(DSS)腰椎稳定术的椎间盘退变疾病(DDD)患者的临床结局及椎间盘再生情况。

文献综述

动态系统在DDD早期可实现再水化。

方法

对2004年至2014年间因节段性不稳定(疼痛性黑椎间盘)接受DSS稳定术的59例患者(平均年龄46.5岁)进行回顾性评估。所有患者术前及术后12个月均接受MRI检查。采用Pfirrmann分类系统对植入节段的椎间盘(IVD)退变程度进行分类。患者平均随访6.4年,临床结局基于视觉模拟量表(VAS)和奥斯威斯功能障碍指数(ODI)评分。

结果

术后6个月(分别为2.85和27.4%)及12个月(分别为1.8和16.3%)时,背痛VAS和ODI评分较术前有显著改善(术前分别为7和68%)。28例患者观察到术后IVD变化。20例患者(3

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddae/5481589/e8b680e7bd4e/asj-11-348-g001.jpg

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