Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Curr Treat Options Oncol. 2017 Jul;18(7):45. doi: 10.1007/s11864-017-0483-z.
The 2016 revision of the WHO classification of lymphoid neoplasms includes new entities along with a clearer definition of provisional and definitive subtypes based on better understanding of the molecular drivers of lymphomas. These changes impact current treatment paradigms and provide a framework for future clinical trials. Additionally, this update recognizes several premalignant or predominantly indolent entities and underscores the importance of avoiding unnecessarily aggressive treatment in the latter subsets.
2016 年版世界卫生组织淋巴造血组织肿瘤分类包括了新的病种，同时根据对淋巴瘤分子驱动因素的更好理解，对暂定和明确的亚型进行了更清晰的定义。这些变化影响了当前的治疗模式，并为未来的临床试验提供了框架。此外，本次更新还认识到了一些潜在恶性或主要惰性的实体肿瘤，并强调了在后一组避免不必要的激进治疗的重要性。
