• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

24 周有氧运动和抗阻训练对伴有肌肉减少性肥胖的老年女性颈动脉内膜中层厚度和血流速度的影响。

Effects of 24-Week Aerobic and Resistance Training on Carotid Artery Intima-Media Thickness and Flow Velocity in Elderly Women with Sarcopenic Obesity.

机构信息

Department of Sport Rehabilitation, Dong Ju College, Busan.

Institute of Taekwondo for Health and Culture, Dong-A University.

出版信息

J Atheroscler Thromb. 2017 Nov 1;24(11):1117-1124. doi: 10.5551/jat.39065. Epub 2017 Jul 1.

DOI:10.5551/jat.39065
PMID:28674320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5684477/
Abstract

AIM

Sarcopenic obesity (SO) is closely associated with cardiovascular disease (CVD) in elderly women. Increases in body fat and decreases in muscle mass are closely associated with increased carotid intima-media thickness (CIMT). The aim of this study was to examine the influence of a 24-week aerobic and resistance training program on carotid parameters in SO.

METHODS

Fifty elderly women (74.1±6.1 years) with SO were randomly divided into an exercise group and a control group. The exercise group performed combined exercise over 24 weeks, consisting of resistance and aerobic training for 50-80 min, 5 times a week. Carotid variables were measured using B-mode ultrasound. The differences in the carotid variables and the relative changes between baseline and after 24 weeks were evaluated.

RESULTS

In the analysis of variance (ANOVA) results, CIMT (p=0.013), systolic flow velocity (p=0.007), diastolic flow velocity (p=0.006), and wall shear rate (p=0.010) showed significant interactions. In paired t-test results of the exercise group, CIMT significantly decreased (p<0.01) and systolic flow velocity (p<0.01), diastolic flow velocity (p<0.001), and wall shear rate (p<0.05) significantly increased after 24 weeks.

CONCLUSION

The 24-week combined exercise effectively decreased CIMT and increased carotid flow velocity and wall shear ratio. Therefore, combined exercise is thought to contribute to the improvement of the risk of CVD in elderly women with SO.

摘要

目的

骨骼肌减少性肥胖(SO)与老年女性的心血管疾病(CVD)密切相关。体脂增加和肌肉质量减少与颈动脉内膜中层厚度(CIMT)增加密切相关。本研究旨在探讨 24 周有氧和抗阻训练对 SO 患者颈动脉参数的影响。

方法

50 名 SO 老年女性(74.1±6.1 岁)被随机分为运动组和对照组。运动组进行 24 周的联合运动,包括每周 5 次、50-80 分钟的抗阻和有氧运动。使用 B 型超声测量颈动脉参数。评估颈动脉参数的差异以及与基线相比 24 周后的相对变化。

结果

在方差分析(ANOVA)结果中,CIMT(p=0.013)、收缩期血流速度(p=0.007)、舒张期血流速度(p=0.006)和壁切率(p=0.010)显示出显著的交互作用。在运动组的配对 t 检验结果中,CIMT 显著降低(p<0.01),收缩期血流速度(p<0.01)、舒张期血流速度(p<0.001)和壁切率(p<0.05)在 24 周后显著增加。

结论

24 周的联合运动可有效降低 CIMT,并增加颈动脉血流速度和壁切率。因此,联合运动被认为有助于改善 SO 老年女性 CVD 的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7b8/5684477/6f5a48bc9c92/jat-24-1117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7b8/5684477/6f5a48bc9c92/jat-24-1117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7b8/5684477/6f5a48bc9c92/jat-24-1117-g001.jpg

相似文献

1
Effects of 24-Week Aerobic and Resistance Training on Carotid Artery Intima-Media Thickness and Flow Velocity in Elderly Women with Sarcopenic Obesity.24 周有氧运动和抗阻训练对伴有肌肉减少性肥胖的老年女性颈动脉内膜中层厚度和血流速度的影响。
J Atheroscler Thromb. 2017 Nov 1;24(11):1117-1124. doi: 10.5551/jat.39065. Epub 2017 Jul 1.
2
Effects of 6 months of aerobic and resistance exercise training on carotid artery intima media thickness in overweight and obese older women.6 个月的有氧运动和抗阻运动训练对超重和肥胖老年女性颈动脉内膜中层厚度的影响。
Geriatr Gerontol Int. 2017 Dec;17(12):2304-2310. doi: 10.1111/ggi.12972. Epub 2017 Jan 6.
3
Carotid Artery Parameters After Combined Exercise Training in Women with Sarcopenic Obesity.肌少性肥胖女性联合运动训练后的颈动脉参数
J Atheroscler Thromb. 2017 Nov 1;24(11):1090-1091. doi: 10.5551/jat.ED085. Epub 2017 Aug 24.
4
Effects of 24-week resistance exercise training on carotid peak systolic and end diastolic flow velocity in healthy older adults.24周抗阻运动训练对健康老年人颈动脉收缩期峰值和舒张末期血流速度的影响。
J Phys Ther Sci. 2016 Oct;28(10):2793-2797. doi: 10.1589/jpts.28.2793. Epub 2016 Oct 28.
5
Effects of Aerobic and Resistance Exercise Training on Carotid Intima-Media Thickness in Abdominal Obese Women.有氧运动和抗阻运动训练对腹型肥胖女性颈动脉内膜中层厚度的影响。
Metab Syndr Relat Disord. 2021 May;19(4):200-204. doi: 10.1089/met.2020.0118. Epub 2021 Mar 15.
6
Effects of exercise training on carotid intima-media thickness in patients with type 2 diabetes and coronary artery disease. Influence of carotid plaques.运动训练对2型糖尿病合并冠状动脉疾病患者颈动脉内膜中层厚度的影响。颈动脉斑块的影响。
Cardiovasc Diabetol. 2016 Jan 22;15:13. doi: 10.1186/s12933-016-0336-2.
7
Body composition influenced by progressive elastic band resistance exercise of sarcopenic obesity elderly women: a pilot randomized controlled trial.渐进式弹性带抗阻运动对老年女性肌少症肥胖患者身体成分的影响:一项初步随机对照试验。
Eur J Phys Rehabil Med. 2017 Aug;53(4):556-563. doi: 10.23736/S1973-9087.17.04443-4. Epub 2017 Jan 12.
8
Exercise training-induced changes in metabolic syndrome parameters, carotid wall thickness, and thyroid function in middle-aged women with subclinical hypothyroidism.运动训练对中年亚临床甲状腺功能减退女性代谢综合征参数、颈动脉壁厚度和甲状腺功能的影响。
Pflugers Arch. 2019 Mar;471(3):479-489. doi: 10.1007/s00424-019-02254-7. Epub 2019 Jan 18.
9
Aerobic exercise training does not alter vascular structure and function in chronic obstructive pulmonary disease.有氧运动训练不会改变慢性阻塞性肺疾病患者的血管结构和功能。
Exp Physiol. 2017 Nov 1;102(11):1548-1560. doi: 10.1113/EP086379. Epub 2017 Sep 30.
10
The independent relationship of epicardial adipose tissue with carotid intima-media thickness and endothelial functions: the association of pulse wave velocity with the active facilitated arterial conduction concept.心外膜脂肪组织与颈动脉内膜中层厚度及内皮功能的独立关系:脉搏波速度与主动易化动脉传导概念的关联
Blood Press Monit. 2013 Apr;18(2):85-93. doi: 10.1097/MBP.0b013e32835ebbb5.

引用本文的文献

1
Effect of five non-invasive treatments on body composition, physical function and quality of life in elderly sarcopenia: a network meta-analysis of 22 randomized controlled trials.五种非侵入性治疗对老年肌少症患者身体成分、身体功能及生活质量的影响:一项对22项随机对照试验的网状Meta分析
Front Physiol. 2025 Aug 25;16:1610138. doi: 10.3389/fphys.2025.1610138. eCollection 2025.
2
Exercise interventions of ≥8 weeks improve body composition, physical function, metabolism, and inflammation in older adults with stage sarcopenic obesity: a systematic review and meta-analysis.为期≥8周的运动干预可改善患有II期肌肉减少性肥胖的老年人的身体成分、身体功能、新陈代谢和炎症:一项系统评价和荟萃分析。
Front Nutr. 2025 Aug 12;12:1575580. doi: 10.3389/fnut.2025.1575580. eCollection 2025.
3

本文引用的文献

1
Effects of exercise training on carotid intima-media thickness in patients with type 2 diabetes and coronary artery disease. Influence of carotid plaques.运动训练对2型糖尿病合并冠状动脉疾病患者颈动脉内膜中层厚度的影响。颈动脉斑块的影响。
Cardiovasc Diabetol. 2016 Jan 22;15:13. doi: 10.1186/s12933-016-0336-2.
2
Carotid flow velocity/diameter ratio is a predictor of cardiovascular events in hypertensive patients.颈动脉血流速度/直径比值是高血压患者心血管事件的一个预测指标。
J Hypertens. 2015 Oct;33(10):2054-60. doi: 10.1097/HJH.0000000000000688.
3
Common carotid artery end-diastolic velocity is independently associated with future cardiovascular events.
Comparative Effectiveness of Exercise, Protein Supplementation, and Combined Interventions for Sarcopenia Management in Women: A Network Meta-Analysis.运动、蛋白质补充剂及联合干预措施对女性肌肉减少症管理的比较效果:一项网状Meta分析
Nutrients. 2025 Jul 22;17(15):2392. doi: 10.3390/nu17152392.
4
Arteries and Hearts in Motion: Sex Differences in Exercise-Mediated Protection Against Atherosclerotic Cardiovascular Disease Risk.运动中的动脉与心脏:运动介导的抗动脉粥样硬化心血管疾病风险保护作用中的性别差异
Curr Atheroscler Rep. 2025 May 16;27(1):56. doi: 10.1007/s11883-025-01300-3.
5
Exercise, Nutrition, and Neuromuscular Electrical Stimulation for Sarcopenic Obesity: A Systematic Review and Meta-Analysis of Management in Middle-Aged and Older Adults.运动、营养与神经肌肉电刺激治疗肌少症肥胖:一项针对中老年人管理的系统评价与荟萃分析
Nutrients. 2025 Apr 29;17(9):1504. doi: 10.3390/nu17091504.
6
Training modalities for elder sarcopenic obesity: a systematic review and network meta-analysis.老年肌少性肥胖的训练方式:一项系统评价和网状Meta分析
Front Nutr. 2025 Feb 19;12:1537291. doi: 10.3389/fnut.2025.1537291. eCollection 2025.
7
Effects of exercise on high-density lipoprotein levels in middle-aged and older individuals: A systematic review and meta-analysis.运动对中老年个体高密度脂蛋白水平的影响:一项系统评价和荟萃分析。
Medicine (Baltimore). 2025 Feb 7;104(6):e41493. doi: 10.1097/MD.0000000000041493.
8
Clinical outcome changes in sarcopenic obesity: a meta-analysis of exercise training methods.肥胖型肌少症的临床结局变化:运动训练方法的荟萃分析
BMC Geriatr. 2025 Jan 15;25(1):33. doi: 10.1186/s12877-024-05655-1.
9
Research Progress on the Effect and Mechanism of Exercise Intervention on Sarcopenia Obesity.运动干预对肌少症肥胖影响及其作用机制的研究进展。
Clin Interv Aging. 2024 Aug 8;19:1407-1422. doi: 10.2147/CIA.S473083. eCollection 2024.
10
Nutritional Management and Physical Activity in the Treatment of Sarcopenic Obesity: A Review of the Literature.营养管理和体力活动在治疗肌少症性肥胖中的作用:文献综述。
Nutrients. 2024 Aug 4;16(15):2560. doi: 10.3390/nu16152560.
颈总动脉舒张末期流速与未来心血管事件独立相关。
Eur J Prev Cardiol. 2016 Jan;23(2):116-24. doi: 10.1177/2047487315571888. Epub 2015 Feb 17.
4
Exercise training in patients with heart failure and preserved ejection fraction: meta-analysis of randomized control trials.心力衰竭且射血分数保留患者的运动训练:随机对照试验的荟萃分析。
Circ Heart Fail. 2015 Jan;8(1):33-40. doi: 10.1161/CIRCHEARTFAILURE.114.001615. Epub 2014 Nov 16.
5
Sarcopenia, sarcopenic obesity and mortality in older adults: results from the National Health and Nutrition Examination Survey III.老年人的肌肉减少症、肌肉减少性肥胖与死亡率:来自第三次全国健康与营养检查调查的结果
Eur J Clin Nutr. 2014 Sep;68(9):1001-7. doi: 10.1038/ejcn.2014.117. Epub 2014 Jun 25.
6
Effects of moderate aerobic exercise training on vascular health and blood pressure in African Americans.中等强度有氧运动训练对非裔美国人血管健康和血压的影响。
J Clin Hypertens (Greenwich). 2014 Jul;16(7):504-10. doi: 10.1111/jch.12328. Epub 2014 Apr 29.
7
Cardiovascular effects of aerobic exercise training in formerly preeclamptic women and healthy parous control subjects.有氧运动训练对既往子痫前期妇女和健康经产妇对照者的心血管影响。
Am J Obstet Gynecol. 2014 Nov;211(5):516.e1-516.e11. doi: 10.1016/j.ajog.2014.04.025. Epub 2014 Apr 23.
8
Effects of six months of combined aerobic and resistance training for elderly patients with a long history of type 2 diabetes.长期患有 2 型糖尿病的老年患者进行 6 个月的有氧和抗阻联合训练的效果。
J Sports Sci Med. 2012 Sep 1;11(3):495-501. eCollection 2012.
9
Sarcopenic obesity as an independent risk factor of hypertension.肌少性肥胖作为高血压的独立危险因素。
J Am Soc Hypertens. 2013 Nov-Dec;7(6):420-5. doi: 10.1016/j.jash.2013.06.002. Epub 2013 Jul 30.
10
Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives.运动在预防心血管疾病中的作用:结果、机制和新视角。
Eur Heart J. 2013 Jun;34(24):1790-9. doi: 10.1093/eurheartj/eht111. Epub 2013 Apr 7.