Institute of Taekwondo for Health and Culture, Dong-A University, Busan, Korea.
Department of Health Care Science, Dong-A University, Busan, Korea.
Geriatr Gerontol Int. 2017 Dec;17(12):2304-2310. doi: 10.1111/ggi.12972. Epub 2017 Jan 6.
We studied the effects of exercise on carotid intima-media thickness, luminal diameter, and flow velocity in overweight and obese older women, and the associations between carotid parameters changes and other variables.
A total of 41 overweight and obese older women (aged 65-77 years, fat mass percent ≥ 32%), who were divided into a control group (n = 20) and a supervised combined exercise group (n = 21). The 24-week combined exercise program (aerobic and resistance exercise) consisted of sessions 40-80 min in length 5 days per week under the supervision of an exercise specialist. Body composition, blood pressure, physical function and carotid variables were assessed. The differences in all variables, and the relative changes between baseline and 24 weeks' follow up were evaluated.
Carotid intima-media thickness, systolic carotid luminal diameter, peak systolic flow velocity and end diastolic flow velocity showed a significant group × time interaction. No interaction was observed for diastolic luminal diameter. In the exercise group, the change of carotid intima-media thickness was significantly associated with systolic blood pressure, maximal walking speed, 1-mile walking time and maximal oxygen uptake. Also, the change of peak systolic flow velocity was significantly associated with skeletal muscle mass, diastolic blood pressure and maximum walking speed.
Combined exercise can effectively improve carotid intima-media thickness in overweight and obese older women. In addition, exercise training increases the systolic carotid luminal diameter and flow velocity in older women. Therefore, regular combined exercise might help prevent atherosclerotic disease by improving the carotid artery. Geriatr Gerontol Int 2017; 17: 2304-2310.
本研究旨在探讨运动对超重和肥胖老年女性颈动脉内膜中层厚度、管腔直径和血流速度的影响，以及颈动脉参数变化与其他变量之间的关系。
共纳入 41 名超重和肥胖老年女性（年龄 65-77 岁，体脂百分比≥32%），分为对照组（n=20）和监督联合运动组（n=21）。24 周的联合运动方案（有氧运动和抗阻运动）由运动专家监督，每周 5 天，每次 40-80 分钟。评估身体成分、血压、身体功能和颈动脉变量。评估所有变量的差异以及基线和 24 周随访之间的相对变化。
颈动脉内膜中层厚度、收缩期颈动脉管腔直径、收缩期峰值血流速度和舒张末期血流速度均显示出显著的组×时间交互作用。舒张期管腔直径无交互作用。在运动组中，颈动脉内膜中层厚度的变化与收缩压、最大步行速度、1 英里步行时间和最大摄氧量显著相关。此外，收缩期峰值血流速度的变化与骨骼肌质量、舒张压和最大步行速度显著相关。
联合运动可有效改善超重和肥胖老年女性的颈动脉内膜中层厚度。此外，运动训练可增加老年女性的收缩期颈动脉管腔直径和血流速度。因此，定期进行联合运动可能通过改善颈动脉来预防动脉粥样硬化疾病。
