烟草（烟草属）中存在免疫反应性和生物活性的类生长抑素物质。

Immunoreactive and bioactive somatostatin-like material is present in tobacco (Nicotiana tabacum).

作者信息

Werner H, Fridkin M, Aviv D, Koch Y

出版信息

Peptides. 1985 Sep-Oct;6(5):797-802. doi: 10.1016/0196-9781(85)90304-3.

Abstract

Immunoreactive and biologically active somatostatin-like material is present in extracts of tobacco plants (Nicotiana tabacum). Comparative chromatographic and immunological characterization of this peptide along with synthetic (hypothalamic-like) somatostatin-14 and -28, indicates that both molecular forms are present in the plant. Tobacco-somatostatin inhibits the prostaglandin E2-induced release of growth hormone from cultured anterior pituitary cells. This finding raises questions concerning the evolutionary mechanisms responsible for the presence of this neuropeptide in plants, and the physiological significance of this phenomena.

摘要

烟草植株（烟草）的提取物中存在免疫反应性和生物活性的类生长抑素物质。对这种肽与合成的（下丘脑样）生长抑素-14和-28进行比较色谱分析和免疫学表征，表明这两种分子形式都存在于植物中。烟草生长抑素可抑制前列腺素E2诱导的培养垂体前叶细胞释放生长激素。这一发现引发了关于植物中存在这种神经肽的进化机制以及这种现象的生理意义的问题。