一种用于探测单细胞IFNγ分泌的膜锚定适配体传感器。
A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells.
作者信息
Qiu Liping, Wimmers Florian, Weiden Jorieke, Heus Hans A, Tel Jurjen, Figdor Carl G
机构信息
Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
出版信息
Chem Commun (Camb). 2017 Jul 13;53(57):8066-8069. doi: 10.1039/c7cc03576d.
Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a cell membrane-anchored sensor for the detection of cytokines secreted by single cells using a combination of aptamer-based sensors and droplet microfluidics.
深入了解单个免疫细胞的行为，特别是细胞因子的分泌，将有助于更深入地理解免疫系统。在这项工作中，我们开发了一种细胞膜锚定传感器，通过结合基于适体的传感器和微滴微流控技术来检测单细胞分泌的细胞因子。
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