Chung Hyun H, Kim Kyeong O, Lee Si H, Jang Byung I, Kim Tae N
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Republic of Korea.
Intern Med J. 2017 Oct;47(10):1184-1189. doi: 10.1111/imj.13542.
BACKGROUND/AIM: The authors aimed to determine the clinical value of colonoscopy by evaluating the frequency of colorectal neoplasm (CRN) detection in patients with early gastric cancer (EGC) as compared with healthy controls and analysed the risk factors of advanced CRN in patients with EGC.
The medical records of 201 patients diagnosed as EGC and age- and gender-matched healthy controls were retrospectively reviewed. Frequencies and clinical features of colorectal polyps of patients and controls were compared. Risk factors of advanced CRN in patients with EGC were also analysed.
Frequencies of CRN in patients and controls were 49.8 and 49.3% respectively (P = 0.90). They were more common in the right colon in patients (P < 0.05). Advanced CRN were found in 10.3% of patients and in 3% of controls (P < 0.05). Multivariate analysis revealed that old age and smoking history were risk factors of an advanced CRN in patients with EGC.
The prevalence of a coexisting advanced CRN was higher in EGC patients. The study shows colonoscopy plays an important role with respect to the detection of synchronous advanced CRN in patients with EGC.
背景/目的：作者旨在通过评估早期胃癌（EGC）患者与健康对照者中大肠肿瘤（CRN）的检出频率来确定结肠镜检查的临床价值，并分析EGC患者中进展期CRN的危险因素。
回顾性分析201例诊断为EGC的患者以及年龄和性别匹配的健康对照者的病历。比较患者和对照者大肠息肉的频率和临床特征。还分析了EGC患者中进展期CRN的危险因素。
患者和对照者中CRN的频率分别为49.8%和49.3%（P = 0.90）。在患者中，CRN在右半结肠更常见（P < 0.05）。10.3%的患者和3%的对照者发现有进展期CRN（P < 0.05）。多因素分析显示，老年和吸烟史是EGC患者进展期CRN的危险因素。
EGC患者中并存进展期CRN的患病率更高。该研究表明结肠镜检查在EGC患者同步进展期CRN的检测中起着重要作用。
