Cahua-Pablo José Ángel, Cruz Miguel, Tello-Almaguer Pedro Vidal, Del Alarcón-Romero Luz Carmen, Parra Esteban Juan, Villerías-Salinas Salvador, Valladares-Salgado Adán, Tello-Flores Vianet Argelia, Méndez-Palacios Abigail, Pérez-Macedonio Claudia Paola, Flores-Alfaro Eugenia
Universidad Autónoma de Guerrero, Facultad de Ciencias Químico Biológicas, Laboratorio de Investigación en Epidemiología Clínica y Molecular, Chilpancingo, Guerrero, 39089, México.
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Bernardo Sepúlveda", Unidad de Investigación Médica en Bioquímica, Ciudad de México, 06725, México.
Am J Hum Biol. 2017 Nov;29(6). doi: 10.1002/ajhb.23032. Epub 2017 Jul 4.
Mexico's current population structure has been defined by admixture between European, Native American, and to some extent African, groups that started in the sixteenth century. The aim of this research was to analyze the relative contributions of these continental population groups to the seven regions of the state of Guerrero, Mexico.
A total of 104 ancestry informative markers were analyzed in 480 unrelated women from the seven regions of the state of Guerrero. The individual ancestry proportions were estimated using the software ADMIXMAP v3.2.
The relative Native American, European and African ancestral contributions to the whole sample were estimated to be 69%, 27%, and 1.9%, respectively. We observed significant differences in admixture proportions across the regions. The highest average Native American ancestry was found in the Montaña region and the lowest in Costa Grande. Conversely, the highest European contribution was observed in Costa Grande. The highest African contributions were observed in the regions of Costa Chica and Costa Grande.
The genetic structure of the population of Guerrero reflects quite well the historical processes that have occurred in this state. Native American population settlements were mainly in the regions of Montaña, Norte, and Centro, where the highest indigenous genetic contribution is observed today. European settlers came from the center of the state to regions with significant agricultural and mining activities. The highest African contributions are observed in coastal regions, in agreement with historical evidence about slave trade routes in the Americas.
墨西哥当前的人口结构是由始于16世纪的欧洲、美洲原住民以及在一定程度上非洲群体之间的混合所定义的。本研究的目的是分析这些大陆人口群体对墨西哥格雷罗州七个地区的相对贡献。
对来自格雷罗州七个地区的480名无关女性分析了总共104个祖先信息标记。使用软件ADMIXMAP v3.2估计个体的祖先比例。
整个样本中美洲原住民、欧洲和非洲祖先的相对贡献估计分别为69%、27%和1.9%。我们观察到各地区的混合比例存在显著差异。在蒙塔纳地区发现美洲原住民血统的平均比例最高，在大科斯塔地区最低。相反，在大科斯塔地区观察到欧洲血统的贡献最高。在小科斯塔和大科斯塔地区观察到非洲血统的贡献最高。
格雷罗州人口的遗传结构很好地反映了该州发生的历史进程。美洲原住民的定居点主要在蒙塔纳、北部和中部地区，如今在这些地区观察到最高的本土遗传贡献。欧洲定居者从该州中部来到有重要农业和采矿活动的地区。在沿海地区观察到非洲血统的贡献最高，这与关于美洲奴隶贸易路线的历史证据一致。
