Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
J Am Acad Dermatol. 2017 Sep;77(3):456-463.e4. doi: 10.1016/j.jaad.2017.04.016. Epub 2017 Jul 1.
Despite recommendations to limit the use of oral antibiotics and increasing support for hormonal agents in the treatment of acne, it is unclear whether there have been any significant changes in practice patterns.
To characterize changes in prescribing behavior for systemic agents in the treatment of acne in the United States between 2004 and 2013.
We conducted a retrospective analysis using the OptumInsight Clinformatics DataMart (Optum, Eden Prairie, MN).
The number of courses of spironolactone prescribed per 100 female patients being managed for acne by dermatologists and nondermatologists increased from 2.08 to 8.13 and from 1.43 to 4.09, respectively. The median duration of therapy with oral antibiotics was 126 and 129 days among patients managed by dermatologists and nondermatologists, respectively, and did not change significantly over the study period.
The OptumInsight Clinformatics DataMart lacks information on acne severity and clinical outcomes.
Additional work to identify patients who would benefit most from alternative therapies such as spironolactone, oral contraceptives, or isotretinoin represents a potential opportunity to improve the care of patients with acne.
尽管有建议限制口服抗生素的使用，并增加对激素药物在痤疮治疗中的支持，但目前尚不清楚实践模式是否发生了任何重大变化。
描述 2004 年至 2013 年期间美国治疗痤疮的全身药物处方行为的变化。
我们使用 OptumInsight Clinformatics DataMart（Optum，明尼苏达州伊登草原）进行了回顾性分析。
皮肤科医生和非皮肤科医生管理的痤疮女性患者中，螺内酯的处方疗程数从每 100 名患者 2.08 增加到 8.13，从每 100 名患者 1.43 增加到 4.09。皮肤科医生和非皮肤科医生管理的患者的口服抗生素治疗的中位疗程分别为 126 天和 129 天，在研究期间没有显著变化。
OptumInsight Clinformatics DataMart 缺乏痤疮严重程度和临床结果的信息。
进一步努力确定最适合接受替代疗法（如螺内酯、口服避孕药或异维 A 酸）的患者，代表了改善痤疮患者护理的潜在机会。
