Department of Dermatology, Yale School of Medicine, New Haven, Connecticut, United States of America.
Program in Translational Biomedicine, Yale School of Medicine, New Haven, Connecticut, United States of America.
PLoS One. 2023 Sep 21;18(9):e0290763. doi: 10.1371/journal.pone.0290763. eCollection 2023.
Acne vulgaris affects a significant number of females into adulthood. Juvenile acne and adult acne have different presentations and potentially distinctive pathogeneses. However, patterns in treatments specifically related to the adult female population have previously not been studied.
Retrospective database analysis of healthcare utilization and medications prescribed for acne using the National Ambulatory Medical Care Survey (NAMCS) data from 2002-2016 was performed.
After age 20, acne accounted for an almost 2.5-fold higher proportion of dermatology visits among females compared to males (10.1% vs. 4.1%, P < 0.001). Tetracycline-class antibiotics were the most prescribed therapy within all age groups of females between 2002-2016. However, there was also a substantial rise in prescriptions of spironolactone beginning in 2012.
A significantly greater proportion of dermatology visits by adult females are for acne in comparison to adult males. Tetracycline-class antibiotics remain the most prescribed therapy in adult age groups despite a potentially different pathogenesis of adult acne. Therefore, there is a need for further studies comparing the effectiveness of therapies specifically for adult female acne.
寻常痤疮影响着大量成年女性。青少年痤疮和成人痤疮的表现不同,潜在的发病机制也可能不同。然而,之前尚未研究过专门针对成年女性人群的治疗模式。
使用 2002-2016 年全国门诊医疗调查(NAMCS)数据,对痤疮的医疗保健利用和处方药物进行回顾性数据库分析。
20 岁以后,与男性相比,女性皮肤科就诊中痤疮的比例几乎高出 2.5 倍(10.1%对 4.1%,P<0.001)。在 2002-2016 年期间,所有年龄段的女性中,四环素类抗生素都是最常用的治疗药物。然而,自 2012 年以来,螺内酯的处方量也大幅增加。
与成年男性相比,成年女性皮肤科就诊中痤疮的比例明显更高。尽管成人痤疮的发病机制可能不同,但四环素类抗生素仍然是成年人群中最常用的治疗药物。因此,需要进一步研究专门针对成年女性痤疮的治疗方法的有效性。