Réus Gislaine Z, Dos Santos Maria Augusta B, Strassi Ana Paula, Abelaira Helena M, Ceretta Luciane B, Quevedo João
Laboratório de Neurociências, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Laboratório de Neurociências, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Life Sci. 2017 Aug 15;183:78-82. doi: 10.1016/j.lfs.2017.06.025. Epub 2017 Jul 1.
Diabetes mellitus (DM) and major depressive disorder (MDD) are diseases that are expanding globally. Separately, each presents with several comorbidities for patients. When the two diseases present simultaneously in the same subject, there is a drastic worsening in the quality of life of the patient. This study reviewed the literature relating to the relationship between MDD and DM, bringing forward studies showing that DM develops due to MDD, and others that report the opposite. According to the studies reviewed, DM and MDD are both debilitating conditions that are associated with significant morbidity, mortality, and healthcare costs. When these two diseases coexist, the association results in a decreased adherence to treatment, poor metabolic control, higher rates of complications, a decrease in the quality of life for the patient, increased healthcare use and cost, increased disability and lost productivity, and an increased risk of death. Therefore, it becomes essential that there are larger studies targeting the association of these two diseases, as for the patient, preventing even one of them will ensure improvements in their quality of life.
糖尿病（DM）和重度抑郁症（MDD）是在全球范围内不断增加的疾病。单独来看，每种疾病都会给患者带来多种合并症。当这两种疾病同时出现在同一患者身上时，患者的生活质量会急剧下降。本研究回顾了与MDD和DM之间关系相关的文献，提出了一些研究表明DM是由MDD引起的，也有其他研究报告了相反的情况。根据所回顾的研究，DM和MDD都是使人衰弱的疾病，与显著的发病率、死亡率和医疗费用相关。当这两种疾病共存时，这种关联会导致治疗依从性降低、代谢控制不佳、并发症发生率更高、患者生活质量下降、医疗使用和费用增加、残疾增加和生产力损失，以及死亡风险增加。因此，针对这两种疾病关联的更大规模研究变得至关重要，因为对于患者来说，预防其中任何一种疾病都将确保其生活质量得到改善。
