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经鼻内镜齿状突切除术治疗颅颈交界区腹侧疾病:多中心经验结果

Endonasal Endoscopic Odontoidectomy in Ventral Diseases of the Craniocervical Junction: Results of a Multicenter Experience.

作者信息

Chibbaro Salvatore, Cebula Helene, Aldea Sorin, Baussart Bertrand, Tigan Leonardo, Todeschi Julien, Romano Antonio, Ganau Mario, Debry Christian, Servadei Franco, Proust Francois, Gaillard Stephane

机构信息

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

出版信息

World Neurosurg. 2017 Oct;106:382-393. doi: 10.1016/j.wneu.2017.06.148. Epub 2017 Jul 1.

Abstract

BACKGROUND

Over the past decades, supported by preliminary anatomic and clinical studies exploring its feasibility and safety, experience has increased of the use of the endoscopic endonasal approach (EEA) to ventral diseases at the craniocervical junction (CCJ).

METHODS

A multicenter study was carried out over a 4-year period of 14 patients managed by EEA odontoidectomy for CCJ diseases causing irreducible atlantoaxial dislocation. The surgical setup included an IGS system based on computed tomography and magnetic resonance images fusion, and 0° and 30° angled endoscopes with dedicated endoscopic tools.

RESULTS

Nine men and 5 women, with a mean age of 60.7 years, were included. The mean follow-up was 28.5 months; 9 patients had basilar impression, whereas 5 had a degenerative pannus. The quality of anterior decompression was excellent in all cases; nonetheless, a posterior stabilization was deemed necessary in 13 patients, and no external orthosis was used during the postoperative course. No tracheostomy or gastrostomy was required after surgery; no deaths, no new neurologic deficits/complications, and no postoperative cerebrospinal fluid leak were recorded. At follow-up, the neurologic status assessed with Frankel grade did not deteriorate in any of the patients but improved in 13 of them; and no new listhesis was shown on neuroradiologic follow-up.

CONCLUSIONS

The results show that EEA provides a direct surgical corridor to the CCJ, allowing an adequate decompression as with the more invasive transoral route. Morbidity is less than with a transoral approach, resulting in higher patient comfort and faster recovery.

摘要

背景

在过去几十年中,在初步解剖学和临床研究探索其可行性和安全性的支持下,经鼻内镜入路(EEA)治疗颅颈交界区(CCJ)腹侧疾病的经验有所增加。

方法

在4年期间对14例因CCJ疾病导致不可复位寰枢椎脱位而行EEA齿状突切除术的患者进行了多中心研究。手术设置包括基于计算机断层扫描和磁共振图像融合的IGS系统,以及带有专用内镜工具的0°和30°角内镜。

结果

纳入9名男性和5名女性,平均年龄60.7岁。平均随访28.5个月;9例患者有基底凹陷,5例有退行性血管翳。所有病例前路减压质量均极佳;尽管如此,13例患者仍认为需要后路稳定,术后过程中未使用外部矫形器。术后无需气管切开或胃造瘘;未记录到死亡、新的神经功能缺损/并发症以及术后脑脊液漏。随访时,根据Frankel分级评估的神经功能状态在任何患者中均未恶化,但13例患者有所改善;神经放射学随访未显示新的椎体滑脱。

结论

结果表明,EEA为CCJ提供了一条直接的手术通道,与更具侵入性的经口途径一样能实现充分减压。发病率低于经口途径,患者舒适度更高,恢复更快。

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