Pereira Armando de Souza, Casseb Livia Medeiros Neves, Barbosa Taciana Fernandes Souza, Begot Alberto Lopes, Brito Roberto Messias Oliveira, Vasconcelos Pedro Fernando da Costa, Travassos da Rosa Elizabeth Salbé
1 Department of Arbovirology and Hemorrhagic Fevers, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde/Ministério da Saúde, Ananindeua, Brazil .
2 Nucleus of Endemic Diseases of the State of Pará - Secretaria de Estado de Saúde Pública do Estado do Pará, Belém, Pará, Brazil .
Vector Borne Zoonotic Dis. 2017 Aug;17(8):576-581. doi: 10.1089/vbz.2016.2010. Epub 2017 Jul 5.
Rabies is an acute, progressive zoonotic viral infection that in general produces a fatal outcome. This disease is responsible for deaths in humans and animals worldwide and, because it can affect all mammals, is considered one of the most important viral infections for public health. This study aimed to determine the prevalence of rabies in bats of different species found in municipalities of the state of Pará from 2005 to 2011. The rabies virus was detected in 12 (0.39%) bats in a total of 3100 analyzed, including hematophagous, frugivorous, and insectivorous bats. Of these, eleven were characterized as AgV3, which is characteristic of the hematophagous bat Desmodus rotundus (E. Geoffroy 1810); one insectivorous animal showed a different profile compatible with the Eptesicus pattern and may therefore be a new antigenic variant. This study identified the need for greater intensification of epidemiological surveillance in municipalities lacking rabies surveillance (silent areas); studies of rabies virus in bats with different alimentary habits, studies investigating the prevalence of AgV3, and prophylactic measures in areas where humans may be infected are also needed.
狂犬病是一种急性、进行性人畜共患病毒感染，通常会导致致命后果。这种疾病在全球范围内导致人类和动物死亡，并且由于它可以感染所有哺乳动物，被认为是对公共卫生最重要的病毒感染之一。本研究旨在确定2005年至2011年在帕拉州各城市发现的不同物种蝙蝠中的狂犬病流行情况。在总共3100只接受分析的蝙蝠中，检测到12只（0.39%）感染了狂犬病病毒，其中包括吸血蝙蝠、食果蝙蝠和食虫蝙蝠。其中，11只被鉴定为AgV3，这是吸血蝙蝠圆叶吸血蝠（E. Geoffroy，1810年）的特征；一只食虫动物表现出与棕蝠模式相符的不同特征，因此可能是一种新的抗原变体。本研究确定，在缺乏狂犬病监测的城市（无声区）需要加强流行病学监测；还需要对具有不同食性的蝙蝠进行狂犬病病毒研究、调查AgV3的流行情况，以及在可能发生人类感染的地区采取预防措施。
