Hermans Michel P, Dath Nicolas
a Cliniques Universitaires Saint-Luc , Brussels , Belgium.
b DBexpertise , Brussels , Belgium.
Acta Clin Belg. 2018 Feb;73(1):68-74. doi: 10.1080/17843286.2017.1348710. Epub 2017 Jul 5.
Most patients with type 2 diabetes mellitus (T2DM) have at least one comorbid chronic disease. These comorbidities increase disease burden and costs and may impact the selection of glucose-lowering therapies. The aim of our study was to describe the prevalence and co-prevalence of comorbidities in patients with T2DM in Belgium.
This was a single centre, transversal, descriptive study performed at Saint-Luc University Hospital, Brussels, Belgium. T2DM patients aged >18 years presenting to the outpatient diabetes clinic and regularly followed (≥1 year) between July 2011 and 2016 were included in the database. Information on descriptive characteristics was collected and several comorbidities were assessed.
Overall, 778 patients were included. The median age was 68 years. The most frequently observed comorbidities were hypertension (85.5%), metabolic syndrome (MetS; 84.6%) and non-alcoholic hepatic steatosis (71.7%). 78.5% of the T2DM patients had ≥4 comorbidities. The highest co-prevalence of comorbidities was the combination of MetS and hypertension (75.8%), MetS and overweight (60.5%), and hypertension and overweight (56.6%).
The observed prevalence and co-prevalence of comorbidities in T2DM Belgian patients was high, with 95.0% patients having at least two comorbid conditions.
大多数2型糖尿病（T2DM）患者至少患有一种合并慢性病。这些合并症增加了疾病负担和成本，并可能影响降糖治疗方案的选择。我们研究的目的是描述比利时T2DM患者中合并症的患病率和共患病率。
这是一项在比利时布鲁塞尔圣吕克大学医院进行的单中心、横断面描述性研究。纳入数据库的患者为2011年7月至2016年期间到门诊糖尿病诊所就诊并定期随访（≥1年）的18岁以上T2DM患者。收集了描述性特征信息并评估了几种合并症。
共纳入778例患者。中位年龄为68岁。最常观察到的合并症为高血压（85.5%）、代谢综合征（MetS；84.6%）和非酒精性肝脂肪变性（71.7%）。78.5%的T2DM患者有≥4种合并症。合并症共患病率最高的是MetS与高血压（75.8%）、MetS与超重（60.5%）以及高血压与超重（56.6%）。
在比利时T2DM患者中观察到的合并症患病率和共患病率很高，95.0%的患者至少有两种合并症。
