Ives Stephen J, Bloom Samuel, Matias Alexs, Morrow Noelle, Martins Natalya, Roh Yookee, Ebenstein Daniel, O'Brien Gabriel, Escudero Daniela, Brito Kevin, Glickman Leah, Connelly Scott, Arciero Paul J
Human Nutrition & Metabolism Laboratory, Health and Exercise Sciences Department, Skidmore College, 815 N. Broadway, Saratoga Springs, NY, 12866, USA.
Scott Connelly Foundation, Corona Del Mar, CA, USA.
J Int Soc Sports Nutr. 2017 Jul 3;14:21. doi: 10.1186/s12970-017-0179-6. eCollection 2017.
An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS). Individually, protein (PRO) and antioxidant (AO) supplementation may improve some aspects of recovery from ECC, though have yet to be combined. We sought to determine if combined PRO and AO supplementation (PRO + AO) improves MS and MF following damaging ECC over PRO alone.
Sixty sedentary college-aged males participated in a randomized, single-blind, parallel design study of peak isometric torque (PIMT), peak isokinetic torque (PIKT), thigh circumference (TC), and muscle soreness (MS) of knee extensor muscles measured at baseline, immediately after and 1, 2, 6, and 24 h after completion of 100 maximal ECC. Immediately, 6 h, and 22 h post-ECC, participants consumed either: carbohydrate control (CHO; = 14), PRO ( = 16), or PRO + AO ( = 17).
At baseline MS, TC, MF, macro- and micro-nutrient intakes, and total work during the ECC were not different between groups ( > 0.05). PIMT and PIKT (both -25%∆), TC (1%∆) and MS (35%∆) all changed with time ( < 0.05). We observed a group by time effect for PIKT (PRO + AO and PRO > CHO, < 0.05). At 24 h post ECC, there was a trend towards improved relative PIMT (11%) and PIKT (17%) for PRO + AO (17%) and PRO (11%) compared to CHO. An interaction indicated PRO + AO had lowest MS over time (PRO + AO > PRO & CHO, < 0.05).
Our results suggest PRO facilitates recovery of muscle function within 24 h following ECC, and addition of AO ameliorates MS more than PRO or CHO alone.
一次急性离心收缩（ECC）会导致肌纤维损伤、炎症、肌肉功能（MF）受损和肌肉酸痛（MS）。单独补充蛋白质（PRO）和抗氧化剂（AO）可能会改善ECC恢复的某些方面，但尚未将两者结合使用。我们试图确定联合补充PRO和AO（PRO + AO）是否比单独补充PRO更能改善ECC损伤后的MS和MF。
60名久坐不动的大学年龄男性参与了一项随机、单盲、平行设计研究，测量了基线时、完成100次最大ECC后立即以及之后1、2、6和24小时的膝关节伸肌的等长峰值扭矩（PIMT）、等速峰值扭矩（PIKT）、大腿围度（TC）和肌肉酸痛（MS）。在ECC后立即、6小时和22小时，参与者分别摄入：碳水化合物对照组（CHO；n = 14）、PRO组（n = 16）或PRO + AO组（n = 17）。
在基线时，各组之间的MS、TC、MF、常量和微量营养素摄入量以及ECC期间的总功没有差异（P>0.05）。PIMT和PIKT（均为-25%∆）、TC（1%∆）和MS（35%∆）均随时间变化（P<0.05）。我们观察到PIKT存在组间×时间效应（PRO + AO组和PRO组>CHO组，P<0.05）。在ECC后24小时，与CHO组相比，PRO + AO组（17%）和PRO组（11%）的相对PIMT（11%）和PIKT（17%）有改善趋势。交互作用表明，随着时间的推移，PRO + AO组的MS最低（PRO + AO组>PRO组和CHO组，P<0.05）。
我们的结果表明，PRO有助于ECC后24小时内肌肉功能的恢复，并且添加AO比单独使用PRO或CHO更能改善MS。
