急性肾损伤时人乳的成分
Composition of human breast milk in acute kidney injury.
作者信息
Chruscicki Adam, Morton Alexander Ross, Akbari Ayub, White Christine Anne
机构信息
Faculty of Medicine, Queen's University, Canada.
Department of Medicine, Queen's University, Canada.
出版信息
Obstet Med. 2017 Jun;10(2):79-82. doi: 10.1177/1753495X16686276. Epub 2017 Jan 29.
BACKGROUND
Breastfeeding is a widely encouraged practice due to its benefits for mother and the infant. Little is known about the impact of disease states, such as kidney dysfunction and childbirth complications, on the composition of breast milk.
METHODS
We describe a case of a 35-year-old woman who suffered a postpartum hemorrhage, was administered a contrast dye prior to computer tomography, and developed an acute kidney injury. Using nuclear magnetic resonance spectrometry, we measured composition of milk in acute kidney injury. The amount of dye secreted into milk was determined using a spectroscopic assay.
RESULTS
Here we show that acute kidney injury results in changes in milk composition, but it does not significantly affect major macronutrients. We also determine that iodinated computer tomography contrast dye does not accumulate in milk in appreciable amounts.
CONCLUSION
Acute kidney injury has impact on breast milk. Intravenous administration of computer tomography contrast dye does not result in significantly elevated levels in milk.
背景
母乳喂养因对母亲和婴儿有益而受到广泛鼓励。关于疾病状态，如肾功能不全和分娩并发症对母乳成分的影响，人们知之甚少。
方法
我们描述了一名35岁女性的病例，她产后出血，在计算机断层扫描前接受了造影剂注射，并发生了急性肾损伤。我们使用核磁共振光谱法测量了急性肾损伤时母乳的成分。通过光谱分析测定了分泌到母乳中的造影剂含量。
结果
我们在此表明，急性肾损伤会导致母乳成分发生变化，但不会显著影响主要常量营养素。我们还确定，碘化计算机断层扫描造影剂不会在母乳中大量蓄积。
结论
急性肾损伤会影响母乳。静脉注射计算机断层扫描造影剂不会导致母乳中造影剂水平显著升高。
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