Santos Luciana, Vericimo Mauricio, Teixeira Gerlinde, Clemente Sergio S, Figueiredo Israel
Departamento de Imunobiologia, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Brazil.
Departamento Tecnologia de Produtos de Origem Animal, Faculdade de Veterinária, Universidade Federal Fluminense, Niterói, Brazil.
Obstet Med. 2017 Jun;10(2):96-98. doi: 10.1177/1753495X16689443. Epub 2017 Feb 1.
This study had sought to assess the seroreactivity to the fish nematode spp. in a puerperal population, as well as to ascertain whether a correlation exists between maternal and cord blood levels.
Blood samples were obtained from puerperal women and cord blood to measure specific anti- antigen IgG and IgE by ELISA. Non-parametric tests were used to compare two or more independent and related samples.
Of the 99 maternal serum samples assessed, 21 were positive on ELISA (21.2%). There were no significant differences in the mean ranks of IgG optical density levels between women who ate fish and those who did not (p = 0.456), those who ate raw fish and those who did not (p = 0.479), or between those who had allergic complaints and those who did not (p = 0.431).
Transplacental passage of antibodies occurred, leading to moderate correlation between maternal and cord blood serum levels.
本研究旨在评估产后人群对鱼类线虫 spp. 的血清反应性,并确定母血和脐血水平之间是否存在相关性。
采集产后妇女和脐血的血样,通过酶联免疫吸附测定法(ELISA)测量特异性抗抗原 IgG 和 IgE。采用非参数检验比较两个或多个独立及相关样本。
在评估的 99 份母血样本中,21 份 ELISA 检测呈阳性(21.2%)。吃鱼的妇女与不吃鱼的妇女之间(p = 0.456)、吃生鱼的妇女与不吃生鱼的妇女之间(p = 0.479),以及有过敏症状的妇女与没有过敏症状的妇女之间(p = 0.431),IgG 光密度水平的平均秩次均无显著差异。
抗体发生了经胎盘传递,导致母血和脐血血清水平之间存在中度相关性。